5-amino-5-(hydroxyimino)-N-((4-(4-phenylthiazol-2-yl)tetrahydro-2H-pyran-4-yl)methyl)pentanamide

Base Information

Chemical Name:5-amino-5-(hydroxyimino)-N-((4-(4-phenylthiazol-2-yl)tetrahydro-2H-pyran-4-yl)methyl)pentanamide
CAS No.:1314887-00-7
Molecular Formula:C₂₀H₂₆N₄O₃S
Molecular Weight:402.517
Hs Code.:

Synonyms:5-amino-5-(hydroxyimino)-N-((4-(4-phenylthiazol-2-yl)tetrahydro-2H-pyran-4-yl)methyl)pentanamide

Suppliers and Price of 5-amino-5-(hydroxyimino)-N-((4-(4-phenylthiazol-2-yl)tetrahydro-2H-pyran-4-yl)methyl)pentanamide

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 5-amino-5-(hydroxyimino)-N-((4-(4-phenylthiazol-2-yl)tetrahydro-2H-pyran-4-yl)methyl)pentanamide

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Technology Process of 5-amino-5-(hydroxyimino)-N-((4-(4-phenylthiazol-2-yl)tetrahydro-2H-pyran-4-yl)methyl)pentanamide

There total 6 articles about 5-amino-5-(hydroxyimino)-N-((4-(4-phenylthiazol-2-yl)tetrahydro-2H-pyran-4-yl)methyl)pentanamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1314886-99-1
4-cyano-N-((4-(4-phenylthiazol-2-yl)tetrahydro-2H-pyran-4-yl)methyl)butanamide

: 1314887-00-7
5-amino-5-(hydroxyimino)-N-((4-(4-phenylthiazol-2-yl)tetrahydro-2H-pyran-4-yl)methyl)pentanamide

Guidance literature:: With hydroxylamine hydrochloride; sodium carbonate; 8-quinolinol; In ethanol; water; for 12h; Reflux;

Reference yield:

: 1314886-98-0
(4-(4-phenylthiazol-2-yl)tetrahydro-2H-pyran-4-yl)methanamine

: 1314887-00-7
5-amino-5-(hydroxyimino)-N-((4-(4-phenylthiazol-2-yl)tetrahydro-2H-pyran-4-yl)methyl)pentanamide

Guidance literature:: Multi-step reaction with 2 steps

1: 4-methyl-morpholine; HATU / N,N-dimethyl-formamide / 4 h / 0 - 20 °C

2: hydroxylamine hydrochloride; sodium carbonate / 8-quinolinol / ethanol; water / 12 h / Reflux

With 4-methyl-morpholine; hydroxylamine hydrochloride; sodium carbonate; HATU; 8-quinolinol; In ethanol; water; N,N-dimethyl-formamide;

Reference yield:

: 70-11-1
α-bromoacetophenone

: 1314887-00-7
5-amino-5-(hydroxyimino)-N-((4-(4-phenylthiazol-2-yl)tetrahydro-2H-pyran-4-yl)methyl)pentanamide

Guidance literature:: Multi-step reaction with 5 steps

1.1: ethanol / 4 h / 80 °C / Reflux

2.1: sodium hydride / tetrahydrofuran; mineral oil / 0.5 h / 0 - 20 °C

2.2: 1 h / 20 °C

3.1: lithium aluminium tetrahydride / tetrahydrofuran / 1 h / 0 - 20 °C

4.1: 4-methyl-morpholine; HATU / N,N-dimethyl-formamide / 4 h / 0 - 20 °C

5.1: hydroxylamine hydrochloride; sodium carbonate / 8-quinolinol / ethanol; water / 12 h / Reflux

With 4-methyl-morpholine; lithium aluminium tetrahydride; hydroxylamine hydrochloride; sodium hydride; sodium carbonate; HATU; 8-quinolinol; In tetrahydrofuran; ethanol; water; N,N-dimethyl-formamide; mineral oil;