methyl 6-chloro-5-formyl-2-methyl-4-(2'-nitrophenyl)-1,4-dihydropyridine-3-carboxylate

Base Information

• Chemical Name: methyl 6-chloro-5-formyl-2-methyl-4-(2'-nitrophenyl)-1,4-dihydropyridine-3-carboxylate
• CAS No.: 882296-26-6
• Molecular Formula: C₁₅H₁₃ClN₂O₅
• Molecular Weight: 336.732
• Mol file: 882296-26-6.mol

Synonyms:methyl 6-chloro-5-formyl-2-methyl-4-(2'-nitrophenyl)-1,4-dihydropyridine-3-carboxylate

Chemical Property of methyl 6-chloro-5-formyl-2-methyl-4-(2'-nitrophenyl)-1,4-dihydropyridine-3-carboxylate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of methyl 6-chloro-5-formyl-2-methyl-4-(2'-nitrophenyl)-1,4-dihydropyridine-3-carboxylate

There total 1 articles about methyl 6-chloro-5-formyl-2-methyl-4-(2'-nitrophenyl)-1,4-dihydropyridine-3-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 69.0%

methyl 1,4,5,6-tetrahydro-2-methyl-4-(2-nitrophenyl)-6-oxo-pyridine-3-carboxylate (130734-39-3) → methyl 6-chloro-5-formyl-2-methyl-4-(2'-nitrophenyl)-1,4-dihydropyridine-3-carboxylate (882296-26-6)

Guidance literature:

methyl 1,4,5,6-tetrahydro-2-methyl-4-(2-nitrophenyl)-6-oxo-pyridine-3-carboxylate; With N,N-dimethyl-formamide; trichlorophosphate; at 50 ℃; for 0.0833333h; Microwave irradiation;

With water; sodium acetate; for 0.5h;

DOI:10.3390/molecules16119620

Reference yield: 65.0%

methyl 6-chloro-5-formyl-2-methyl-4-(2'-nitrophenyl)-1,4-dihydropyridine-3-carboxylate (882296-26-6) → 6-Chlor-5-formyl-2-methyl-4-(2-nitrophenyl)nicotinsaeuremethylester (882296-28-8)

Guidance literature:

With ammonium cerium(IV) nitrate; In water; acetone; for 0.666667h;

Reference yield: 42.0%

methyl 6-chloro-5-formyl-2-methyl-4-(2'-nitrophenyl)-1,4-dihydropyridine-3-carboxylate (882296-26-6) + methanol (67-56-1) → (E)-5-Methoxymethylen-2-methyl-4-(2-nitrophenyl)-6-oxo-1,4,5,6-tetrahydropyridin-3-carbonsaeuremethylester

Guidance literature:

In methanol; for 2h; UV-irradiation;

upstream raw materials:

methyl 1,4,5,6-tetrahydro-2-methyl-4-(2-nitrophenyl)-6-oxo-pyridine-3-carboxylate

Downstream raw materials:

6-Chlor-5-formyl-2-methyl-4-(2-nitrophenyl)nicotinsaeuremethylester

6-Chlor-2-methyl-4-(2-nitrophenyl)-5-{(E/Z)-[(2-sulfanylphenyl)imino]methyl}nicotinsaeuremethylester