(RS)-cyclohexyl methyl ketone cyanohydrin

Base Information

• Chemical Name: (RS)-cyclohexyl methyl ketone cyanohydrin
• CAS No.: 69440-66-0
• Molecular Formula: C₉H₁₅NO
• Molecular Weight: 153.224
• Mol file: 69440-66-0.mol

Synonyms:(RS)-cyclohexyl methyl ketone cyanohydrin

Chemical Property of (RS)-cyclohexyl methyl ketone cyanohydrin

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (RS)-cyclohexyl methyl ketone cyanohydrin

There total 2 articles about (RS)-cyclohexyl methyl ketone cyanohydrin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

trimethylsilyl cyanide (7677-24-9) + Cyclohexyl methyl ketone (823-76-7) → (RS)-cyclohexyl methyl ketone cyanohydrin (69440-66-0)

Guidance literature:

With hydrogenchloride; copper(II) bis(trifluoromethanesulfonate); Yield given. Multistep reaction; 1.) MeCN, r.t., 3 h; 2.) MeCN, 0 deg C;

DOI:10.1016/S0040-4039(98)00594-2

Reference yield:

potassium cyanide + rac-1-cyclohexylethanol (1193-81-3) → (RS)-cyclohexyl methyl ketone cyanohydrin (69440-66-0)

Guidance literature:

With sodium disulfite;

DOI:10.1021/jo100445d

Reference yield:

ethanol (64-17-5) + (RS)-cyclohexyl methyl ketone cyanohydrin (69440-66-0) → hydrogen cyanide (74-90-8) + Cyclohexyl methyl ketone (823-76-7)

Guidance literature:

at 20 ℃; Equilibrium constant; sowie bei 35grad;

DOI:10.1039/jr9540001310

upstream raw materials:

trimethylsilyl cyanide

Cyclohexyl methyl ketone

rac-1-cyclohexylethanol

Downstream raw materials:

hydrogen cyanide

Cyclohexyl methyl ketone