4-Hydroxy-2-butanone

Base Information

Chemical Name:4-Hydroxy-2-butanone
CAS No.:590-90-9
Molecular Formula:C4H8O2
Molecular Weight:88.1063
Hs Code.:29144000
European Community (EC) Number:209-693-6
NSC Number:41219
UNII:TCM0BJ44MF
DSSTox Substance ID:DTXSID4060442
Nikkaji Number:J24.210A
Wikidata:Q27094939
Metabolomics Workbench ID:148567
Mol file:590-90-9.mol

Synonyms:4-hydroxy-2-butanone;4H2B compound

Suppliers and Price of 4-Hydroxy-2-butanone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Acrotein
4-Hydroxybutan-2-one 97%
250g
$ 220.00

AK Scientific
4-Hydroxy-2-butanone
5g
$ 15.00

Alfa Aesar
4-Hydroxy-2-butanone, 95%
25g
$ 49.30

Alfa Aesar
4-Hydroxy-2-butanone, 95%
100g
$ 127.00

American Custom Chemicals Corporation
4-HYDROXY-2-BUTANONE 95.00%
1G
$ 605.15

American Custom Chemicals Corporation
4-HYDROXY-2-BUTANONE 95.00%
2.5G
$ 769.05

American Custom Chemicals Corporation
4-HYDROXY-2-BUTANONE 95.00%
5G
$ 859.90

Frontier Specialty Chemicals
4-Hydroxy-2-butanone 95%
100g
$ 101.00

Frontier Specialty Chemicals
4-Hydroxy-2-butanone 95%
25g
$ 34.00

Oakwood
4-Hydroxybutan-2-one
100g
$ 95.00

Total 156 raw suppliers

Chemical Property of 4-Hydroxy-2-butanone

Chemical Property:

Appearance/Colour:Colorless liquid
Vapor Pressure:1.05mmHg at 25°C
Melting Point:15°C (estimate)
Refractive Index:1.430
Boiling Point:156.3 °C at 760 mmHg
PKA:14.43±0.10(Predicted)
Flash Point:55.5 °C
PSA：37.30000
Density:0.987 g/cm³
LogP:-0.04220
Storage Temp.:under inert gas (nitrogen or Argon) at 2-8°C
Solubility.:Chloroform, Methanol (Slightly)
Water Solubility.:Miscible with water, alcohol, ethanol and ether.
XLogP3:-0.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:88.052429494
Heavy Atom Count:6
Complexity:49.5

Purity/Quality:

99% ^*data from raw suppliers

4-Hydroxybutan-2-one 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s): R10:;
Hazard Codes:R10:;
Statements: 10
Safety Statements: 16-24/25

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

Chemical Classes:Solvents -> Other Solvents
Canonical SMILES:CC(=O)CCO
Uses 4-Hydroxy-2-butanone is used in the preparation of fused benzazepine molecules as selective D3 receptor antagonists with pharmaceutical activity. It is also used in the preparation of verrucarin and mevalonic acid lactone. Further, it is used to prepare 3-buten-2-one through dehydration over an anatase titanium dioxide catalyst. It is also employed in the preparation of 4-methyl-5-hydroxymethylthiazole, (±)-lineatin and beta-hydroxylactones.

Technology Process of 4-Hydroxy-2-butanone

There total 69 articles about 4-Hydroxy-2-butanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 927-74-2
3-Butyn-1-ol

: 590-90-9
1-Hydroxy-3-butanone

Guidance literature:: With silver hexafluoroantimonate; disodium chloro[1,3-bis(2,6-diisopropyl-4-sodiumsulfonatophenyl)imidazol-2-ylidene]gold(I); water; at 60 ℃; for 2h;
DOI:10.1039/c5cy01278c