N-tosyl-2-((E)-styryl)aziridine

Base Information

• Chemical Name: N-tosyl-2-((E)-styryl)aziridine
• CAS No.: 1590339-98-2
• Molecular Formula: C₁₇H₁₇NO₂S
• Molecular Weight: 299.393
• Mol file: 1590339-98-2.mol

Synonyms:N-tosyl-2-((E)-styryl)aziridine

Chemical Property of N-tosyl-2-((E)-styryl)aziridine

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of N-tosyl-2-((E)-styryl)aziridine

There total 5 articles about N-tosyl-2-((E)-styryl)aziridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 63.0%

buta-1,3-dien-1-ylbenzene (1515-78-2) + [N-(p-tolylsulfonyl)imino]phenyliodinane (55962-05-5) → N-tosyl-2-((E)-styryl)aziridine (1590339-98-2)

Guidance literature:

With copper acetylacetonate; In acetonitrile; at 20 ℃; for 0.5h; Inert atmosphere; Schlenk technique;

DOI:10.1021/acs.orglett.9b03672

Reference yield: 33.0%

(E)-buta-1,3-dienylbenzene (16939-57-4) + [N-(p-tolylsulfonyl)imino]phenyliodinane (55962-05-5) → N-tosyl-2-((E)-styryl)aziridine (1590339-98-2)

Guidance literature:

With [Cu₃(benzene 1,3,5-tricarboxylate)₂(H₂O)₃]_n thermal activated at 120 °C; In acetonitrile; at 20 ℃; for 2h; regioselective reaction; Molecular sieve; Inert atmosphere;

DOI:10.1021/acs.inorgchem.1c00201

Reference yield: 11.0%

(E)-buta-1,3-dienylbenzene (16939-57-4) + toluene-4-sulfonamide (70-55-3) → N-tosyl-2-((E)-styryl)aziridine (1590339-98-2)

Guidance literature:

With tetrakis(actonitrile)copper(I) hexafluorophosphate; iodosylbenzene; In acetonitrile; at 0 - 23 ℃; Molecular sieve; Inert atmosphere;

DOI:10.1002/chem.201303699

upstream raw materials:

(E)-buta-1,3-dienylbenzene

N-(phenylsulfonylimino)-phenyl-λ³-iodane

toluene-4-sulfonamide

buta-1,3-dien-1-ylbenzene