N-(2-propyl)-4-methoxybenzylideneamine

Base Information

• Chemical Name: N-(2-propyl)-4-methoxybenzylideneamine
• CAS No.: 13033-52-8
• Molecular Formula: C₁₁H₁₅NO
• Molecular Weight: 177.246
• Mol file: 13033-52-8.mol

Synonyms:N-(2-propyl)-4-methoxybenzylideneamine

Chemical Property of N-(2-propyl)-4-methoxybenzylideneamine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N-(2-propyl)-4-methoxybenzylideneamine

There total 7 articles about N-(2-propyl)-4-methoxybenzylideneamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

4-methoxy-benzaldehyde (123-11-5) + isopropylamine (75-31-0) → N-(2-propyl)-4-methoxybenzylideneamine (13033-52-8)

Guidance literature:

In chloroform; at 20 ℃; for 24h;

DOI:10.1039/c6cc09379e

Reference yield: 60.0%

isopropylamine (75-31-0) + 4-Methoxybenzyl alcohol (105-13-5) → N-(2-propyl)-4-methoxybenzylideneamine (13033-52-8)

Guidance literature:

With potassium tert-butylate; [Ru(η⁶-p-cymene)(1-(5-methylthiazole-2-yl)-3-phenylthiourea)]₂Cl₂; In toluene; at 60 ℃; for 12h; Green chemistry;

DOI:10.1002/aoc.6122

Reference yield:

4-methoxy-N-(1-methylethyl)benzamide (7464-44-0) → N-(2-propyl)-4-methoxybenzylideneamine (13033-52-8)

Guidance literature:

4-methoxy-N-(1-methylethyl)benzamide; With 2-fluoropyridine; trifluoromethylsulfonic anhydride; In dichloromethane; at 0 ℃; for 0.333333h; Inert atmosphere;

With 1,1,3,3-Tetramethyldisiloxane; In dichloromethane; at 0 - 20 ℃; for 6.16667h; Inert atmosphere;

DOI:10.1007/s11426-016-0224-5

upstream raw materials:

C₁₁H₁₆ClNO

4-methoxy-benzaldehyde

isopropylamine

4-methoxy-N-(1-methylethyl)benzamide

Downstream raw materials:

[(4-methoxyphenyl)methyl](propan-2-yl)amine

(4R,5R)-5-Hydroxymethyl-4-(4-methoxy-phenyl)-2-oxy-4,5-dihydro-isoxazole-3-carboxylic acid methyl ester

2-[dimethoxy(4-methoxyphenyl)methyl]-1-isopropylaziridine

3,3-dichloro-1-isopropyl-2-(4-methoxyphenyl)azetidine

Refernces

• 1、 Quntar, Abed Al Aziz Al,Dembitsky, Valery M.,Srebnik, Morris. "Novel one-pot synthesis of 3-amino-1-alkenylphophonates by addition of imines to alkynylphosphonate titanium(II) complexes". . p. 357 - 359. Retrieved 2003.
• 2、 Sobanov,Zolotukhin,Galkin,Cherkasov,Pudovik. "Kinetics and mechanism of the Pudovik reaction in the azomethine series: I. Addition of dimethyl hydrogen phosphite to N-isopropylbenzalimines". . p. 1067 - 1070. Retrieved 2002.
• 3、 Koch, Vanessa,Lorion, Mélanie M.,Barde, Etienne,Br?se, Stefan,Cossy, Janine. "Cobalt-Catalyzed α-Arylation of Substituted α-Halogeno β-Lactams". supporting information. p. 6241 - 6244. Retrieved 2019/08/26.