5-(2-Iodo-3-methoxyphenoxy)-2(5H)-furanone

Base Information

Chemical Name:5-(2-Iodo-3-methoxyphenoxy)-2(5H)-furanone
CAS No.:121980-51-6
Molecular Formula:C₁₁H₉IO₄
Molecular Weight:332.095
Hs Code.:
DSSTox Substance ID:DTXSID701267622

Synonyms:5-(2-Iodo-3-methoxyphenoxy)-2(5H)-furanone;DTXSID701267622;121980-51-6

Suppliers and Price of 5-(2-Iodo-3-methoxyphenoxy)-2(5H)-furanone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 5-(2-Iodo-3-methoxyphenoxy)-2(5H)-furanone

Chemical Property:

XLogP3:2.6
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:331.95456
Heavy Atom Count:16
Complexity:292

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:COC1=C(C(=CC=C1)OC2C=CC(=O)O2)I

Technology Process of 5-(2-Iodo-3-methoxyphenoxy)-2(5H)-furanone

There total 2 articles about 5-(2-Iodo-3-methoxyphenoxy)-2(5H)-furanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 57234-28-3
1-methoxy-3-(methoxymethoxy)benzene

: 121980-51-6
5-(2-Iodo-3-methoxy-phenoxy)-5H-furan-2-one

Guidance literature:: Multi-step reaction with 2 steps

1: 1) t-BuLi, TMEDA, I₂, 2) TFA / 1) Et₂O, -78 deg C, 2) CH₂Cl₂, r.t.

2: K₂CO₃ / acetone / Heating

With N,N,N,N,-tetramethylethylenediamine; iodine; tert.-butyl lithium; potassium carbonate; trifluoroacetic acid; In acetone;
DOI:10.1016/S0040-4039(00)80580-8