diisopropyl 2-(phenyl-λ³-iodanylidene)malonate

Base Information

• Chemical Name: diisopropyl 2-(phenyl-λ³-iodanylidene)malonate
• CAS No.: 1093350-32-3
• Molecular Formula: C₁₅H₁₉IO₄
• Molecular Weight: 390.218
• Mol file: 1093350-32-3.mol

Synonyms:diisopropyl 2-(phenyl-λ³-iodanylidene)malonate

Chemical Property of diisopropyl 2-(phenyl-λ³-iodanylidene)malonate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of diisopropyl 2-(phenyl-λ³-iodanylidene)malonate

There total 3 articles about diisopropyl 2-(phenyl-λ³-iodanylidene)malonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 76.0%

diisopropyl malonate (13195-64-7) + [bis(acetoxy)iodo]benzene (3240-34-4) → diisopropyl 2-(phenyl-λ3-iodanylidene)malonate (1093350-32-3)

Guidance literature:

diisopropyl malonate; With potassium hydroxide; In dichloromethane; at 20 ℃; for 0.0833333h; Inert atmosphere;

[bis(acetoxy)iodo]benzene; In dichloromethane; at 20 ℃; for 2h; Inert atmosphere;

DOI:10.1021/jo802208q

Reference yield:

diisopropyl malonate (13195-64-7) + iodosylbenzene (536-80-1) → diisopropyl 2-(phenyl-λ3-iodanylidene)malonate (1093350-32-3)

Guidance literature:

With potassium hydroxide; In dichloromethane; at 20 ℃; for 2h; Inert atmosphere;

DOI:10.1021/jo802208q

Reference yield:

iodobenzene (591-50-4) → diisopropyl 2-(phenyl-λ3-iodanylidene)malonate (1093350-32-3)

Guidance literature:

Multi-step reaction with 2 steps

1: Selectfluor

2: potassium hydroxide

With Selectfluor; potassium hydroxide;

DOI:10.1002/chem.201504852

upstream raw materials:

diisopropyl malonate

[bis(acetoxy)iodo]benzene

iodosylbenzene

iodobenzene

Downstream raw materials:

diisopropyl 2-phenylcyclopropane-1,1-dicarboxylate

diisopropyl (2S)-2-phenylcyclopropane-1,1-dicarboxylate

1-(1,2-diphenylethoxy)-2,2,6,6-tetramethylpiperidine