N-{2-methoxy-5-[6-(2-methoxy-phenyl)-pyrimidin-4-ylamino]-phenyl}-formamide

Base Information

Chemical Name:N-{2-methoxy-5-[6-(2-methoxy-phenyl)-pyrimidin-4-ylamino]-phenyl}-formamide
CAS No.:1569983-52-3
Molecular Formula:C₁₉H₁₈N₄O₃
Molecular Weight:350.377
Hs Code.:

Synonyms:N-{2-methoxy-5-[6-(2-methoxy-phenyl)-pyrimidin-4-ylamino]-phenyl}-formamide

Suppliers and Price of N-{2-methoxy-5-[6-(2-methoxy-phenyl)-pyrimidin-4-ylamino]-phenyl}-formamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of N-{2-methoxy-5-[6-(2-methoxy-phenyl)-pyrimidin-4-ylamino]-phenyl}-formamide

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of N-{2-methoxy-5-[6-(2-methoxy-phenyl)-pyrimidin-4-ylamino]-phenyl}-formamide

There total 6 articles about N-{2-methoxy-5-[6-(2-methoxy-phenyl)-pyrimidin-4-ylamino]-phenyl}-formamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 33.0%

: 64-18-6
formic acid

: 1569981-66-3
4-methoxy-N¹-(6-(2-methoxyphenyl)pyrimidin-4-yl)benzene-1,3-diamine

: 1569983-52-3
N-{2-methoxy-5-[6-(2-methoxy-phenyl)-pyrimidin-4-ylamino]-phenyl}-formamide

Guidance literature:: With pyridine; In dichloromethane; acetic anhydride; at 0 - 20 ℃;

Reference yield:

: 364-76-1
4-Fluoro-3-nitroaniline

: 1569983-52-3
N-{2-methoxy-5-[6-(2-methoxy-phenyl)-pyrimidin-4-ylamino]-phenyl}-formamide

Guidance literature:: Multi-step reaction with 4 steps

1.1: sodium / 72 h / Reflux

1.2: 0.5 h / 0 °C

2.1: tert-butyl alcohol / 6 h / Reflux

3.1: triethylamine; palladium 10% on activated carbon; hydrogen / methanol; dichloromethane / 20 °C

4.1: pyridine / dichloromethane; acetic anhydride / 0 - 20 °C

With pyridine; palladium 10% on activated carbon; hydrogen; sodium; triethylamine; In methanol; dichloromethane; acetic anhydride; tert-butyl alcohol;

Reference yield:

: 75634-03-6
4-chloro-6-(2-methoxy-phenyl)-pyrimidine

: 1569983-52-3
N-{2-methoxy-5-[6-(2-methoxy-phenyl)-pyrimidin-4-ylamino]-phenyl}-formamide

Guidance literature:: Multi-step reaction with 3 steps

1: tert-butyl alcohol / 6 h / Reflux

2: triethylamine; palladium 10% on activated carbon; hydrogen / methanol; dichloromethane / 20 °C

3: pyridine / dichloromethane; acetic anhydride / 0 - 20 °C

With pyridine; palladium 10% on activated carbon; hydrogen; triethylamine; In methanol; dichloromethane; acetic anhydride; tert-butyl alcohol;