2-ethyl-2-phenylcyclohexanone

Base Information

• Chemical Name: 2-ethyl-2-phenylcyclohexanone
• CAS No.: 17206-56-3
• Molecular Formula: C₁₄H₁₈O
• Molecular Weight: 202.296
• Mol file: 17206-56-3.mol

Synonyms:2-ethyl-2-phenylcyclohexanone

Chemical Property of 2-ethyl-2-phenylcyclohexanone

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-ethyl-2-phenylcyclohexanone

There total 7 articles about 2-ethyl-2-phenylcyclohexanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.0%

(RS)-2-phenylcyclohexanone (1444-65-1) + ethyl iodide (75-03-6) → 2-ethyl-2-phenylcyclohexanone (17206-56-3)

Guidance literature:

(RS)-2-phenylcyclohexanone; With potassium tert-butylate; In tert-butyl alcohol; for 0.75h;

ethyl iodide; In tert-butyl alcohol; at 20 ℃; for 2.5h;

DOI:10.1021/acs.joc.7b00802

Reference yield:

2-Aethyl-2-phenyl-heptan-dinitril (15595-70-7) → 2-ethyl-2-phenylcyclohexanone (17206-56-3)

Guidance literature:

Multi-step reaction with 2 steps

1: LiNEt₂ / diethyl ether

2: aq. HCl

With hydrogenchloride; lithium diethylamide; In diethyl ether;

DOI:10.1139/v67-315

Reference yield:

(+/-)-2-Ethyl-6-chlor-2-phenyl-hexansaeurenitril (1705-61-9) → 2-ethyl-2-phenylcyclohexanone (17206-56-3)

Guidance literature:

Multi-step reaction with 3 steps

1: dimethylsulfoxide

2: LiNEt₂ / diethyl ether

3: aq. HCl

With hydrogenchloride; lithium diethylamide; In diethyl ether; dimethyl sulfoxide;

DOI:10.1139/v67-315

upstream raw materials:

ethyl bromide

(RS)-2-phenylcyclohexanone

ethyl iodide

1-Cyan-2-imino-3-phenyl-3-ethyl-cyclohexan

Downstream raw materials:

6-phenyloctanoic acid

racem-2-Ethyl-6,6-dimethyl-2-phenylcyclohexanon

2-ethyl-2-phenyl-cyclohexanol

1-(1-ethylcyclohexyl)benzene

Refernces