dicyclohexyl phosphorochloridate

Base Information

• Chemical Name: dicyclohexyl phosphorochloridate
• CAS No.: 51672-37-8
• Molecular Formula: C₁₂H₂₂ClO₃P
• Molecular Weight: 280.732
• Mol file: 51672-37-8.mol

Synonyms:dicyclohexyl phosphorochloridate

Chemical Property of dicyclohexyl phosphorochloridate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of dicyclohexyl phosphorochloridate

There total 4 articles about dicyclohexyl phosphorochloridate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

cyclohexanol (108-93-0) → dicyclohexyl phosphorochloridate (51672-37-8)

Guidance literature:

cyclohexanol; With n-butyllithium; In tetrahydrofuran; diethyl ether; at -30 ℃; for 0.166667h; Inert atmosphere; Schlenk technique;

With trichlorophosphate; In tetrahydrofuran; diethyl ether; at -30 - 20 ℃; Inert atmosphere; Schlenk technique;

DOI:10.1021/om500953c

Reference yield: 96.0%

dicyclohexyl phosphonate (3808-22-8) → dicyclohexyl phosphorochloridate (51672-37-8)

Guidance literature:

With trichloroisocyanuric acid; In acetonitrile; at 20 ℃;

DOI:10.1016/j.tetlet.2005.06.024

Reference yield: 62.5%

tricyclohexyl phosphite (15205-58-0) → dicyclohexyl phosphorochloridate (51672-37-8)

Guidance literature:

With 1,3-dimethyl-2-imidazolidinone; bis(trichloromethyl) carbonate; In dichloromethane; at 0 - 35 ℃; for 3.5h;

upstream raw materials:

N-chloro-succinimide

dicyclohexyl phosphonate

tricyclohexyl phosphite

cyclohexanol

Downstream raw materials:

Dicyclohexyl-tert.-butylperoxyphosphat

Phosphoric acid (E)-6-(tert-butyl-dimethyl-silanyloxy)-1-isopropenyl-4-methyl-hex-4-enyl ester dicyclohexyl ester

C₄₆H₇₅O₁₂P

dicyclohexyl phosphorofluoridate

Refernces

• 1、 Korb, Marcus,Lang, Heinrich. "Planar chirality from the chiral pool: Diastereoselective anionic phospho-fries rearrangements at ferrocene". . p. 6643 - 6659. Retrieved 2015/02/19.
• 2、 Santschi, Nico,Geissbühler, Patrik,Togni, Antonio. "Reactivity of an electrophilic hypervalent iodine trifluoromethylation reagent with hydrogen phosphates - A mechanistic study". experimental part. p. 83 - 86. Retrieved 2012/03/27.