<2S<2α(1R,2S),3β>>-2-<4-(1,3-dioxolan-2yl)-1-methyl-2-<(phenylmethoxy)methoxy>butyl>-2,3-dihydro-3,5-dimethyl-4H-pyran-4-one

Base Information

Chemical Name:<2S<2α(1R*,2S*),3β>>-2-<4-(1,3-dioxolan-2yl)-1-methyl-2-<(phenylmethoxy)methoxy>butyl>-2,3-dihydro-3,5-dimethyl-4H-pyran-4-one
CAS No.:106734-75-2
Molecular Formula:C₂₃H₃₂O₆
Molecular Weight:404.503
Hs Code.:

Synonyms:<2S<2α(1R*,2S*),3β>>-2-<4-(1,3-dioxolan-2yl)-1-methyl-2-<(phenylmethoxy)methoxy>butyl>-2,3-dihydro-3,5-dimethyl-4H-pyran-4-one

Suppliers and Price of <2S<2α(1R*,2S*),3β>>-2-<4-(1,3-dioxolan-2yl)-1-methyl-2-<(phenylmethoxy)methoxy>butyl>-2,3-dihydro-3,5-dimethyl-4H-pyran-4-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of <2S<2α(1R*,2S*),3β>>-2-<4-(1,3-dioxolan-2yl)-1-methyl-2-<(phenylmethoxy)methoxy>butyl>-2,3-dihydro-3,5-dimethyl-4H-pyran-4-one

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of <2S<2α(1R*,2S*),3β>>-2-<4-(1,3-dioxolan-2yl)-1-methyl-2-<(phenylmethoxy)methoxy>butyl>-2,3-dihydro-3,5-dimethyl-4H-pyran-4-one

There total 6 articles about <2S<2α(1R*,2S*),3β>>-2-<4-(1,3-dioxolan-2yl)-1-methyl-2-<(phenylmethoxy)methoxy>butyl>-2,3-dihydro-3,5-dimethyl-4H-pyran-4-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

: 72486-93-2
1-methoxy-2-methyl-3-trimethylsiloxy-1,3-pentadiene

: 106734-74-1
-α-methyl-β-<(phenylmethoxy)methoxy>-1,3-dioxolane-2-pentanal

: 106734-75-2
<2S<2α(1R*,2S*),3β>>-2-<4-(1,3-dioxolan-2yl)-1-methyl-2-<(phenylmethoxy)methoxy>butyl>-2,3-dihydro-3,5-dimethyl-4H-pyran-4-one

Guidance literature:: With magnesium bromide; In diethyl ether; dichloromethane; benzene; for 5h; -65 deg C then to 0 deg C;
DOI:10.1021/ja00221a043

Reference yield:

: 3587-60-8
Benzyloxymethyl chloride

: 106734-75-2
<2S<2α(1R*,2S*),3β>>-2-<4-(1,3-dioxolan-2yl)-1-methyl-2-<(phenylmethoxy)methoxy>butyl>-2,3-dihydro-3,5-dimethyl-4H-pyran-4-one

Guidance literature:: Multi-step reaction with 3 steps

1: 91 percent / diisopropylamine / 16 h / Ambient temperature

2: 1.) ozone, sodium bicarbonate; 2.) dimethyl sulfide, Zn, AcOH / 1.) CH₂Cl₂, CH₃OH, -78 deg C, 20 min; 2.) room temp.

3: 80 percent / MgBr₂*OEt₂ / CH₂Cl₂; diethyl ether; benzene / 5 h / -65 deg C then to 0 deg C

With dimethylsulfide; sodium hydrogencarbonate; ozone; acetic acid; diisopropylamine; magnesium bromide; zinc; In diethyl ether; dichloromethane; benzene;
DOI:10.1021/ja00221a043

Reference yield:

: 37610-80-3
1,3-dioxolan-2-ylethylmagnesium bromide

: 106734-75-2
<2S<2α(1R*,2S*),3β>>-2-<4-(1,3-dioxolan-2yl)-1-methyl-2-<(phenylmethoxy)methoxy>butyl>-2,3-dihydro-3,5-dimethyl-4H-pyran-4-one

Guidance literature:: Multi-step reaction with 5 steps

1: 90 percent / tetrahydrofuran / -78 deg C then 0 deg C

2: 74 percent / sodium hydride / tetrahydrofuran; hexamethylphosphoric acid triamide / 22 h / Ambient temperature

3: 91 percent / diisopropylamine / 16 h / Ambient temperature

4: 1.) ozone, sodium bicarbonate; 2.) dimethyl sulfide, Zn, AcOH / 1.) CH₂Cl₂, CH₃OH, -78 deg C, 20 min; 2.) room temp.

5: 80 percent / MgBr₂*OEt₂ / CH₂Cl₂; diethyl ether; benzene / 5 h / -65 deg C then to 0 deg C

With dimethylsulfide; sodium hydride; sodium hydrogencarbonate; ozone; acetic acid; diisopropylamine; magnesium bromide; zinc; In tetrahydrofuran; N,N,N,N,N,N-hexamethylphosphoric triamide; diethyl ether; dichloromethane; benzene;
DOI:10.1021/ja00221a043