2-amino-3-benzoyl-α-(1-propylthio)-benzeneacetamide

Base Information

• Chemical Name: 2-amino-3-benzoyl-α-(1-propylthio)-benzeneacetamide
• CAS No.: 173262-94-7
• Molecular Formula: C₁₈H₂₀N₂O₂S
• Molecular Weight: 328.435
• Mol file: 173262-94-7.mol

Synonyms:2-amino-3-benzoyl-α-(1-propylthio)-benzeneacetamide

Chemical Property of 2-amino-3-benzoyl-α-(1-propylthio)-benzeneacetamide

Chemical Property:

Purity/Quality:

>95% ^*data from raw suppliers

2-Amino-3-benzoyl-α-(propylthio)benzeneacetamide ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Uses: 2-Amino-3-benzoyl-α-(propylthio)benzeneacetamide is derived from Methyl Chloroacetate (M294960), which is widely used in the chemical and biochemical fields as an extraction solvent. Methyl Chloroacetate is known to induce DNA damage to rat sperm, and is also thought to be toxic to humans upon exposure. Methyl chloroacetate is also used as a reagent to synthesize Valdecoxib (V090000), a selective cyclooxygenase 2(COX-2) specific inhibitor that is used to treat postoperative pain;Also, it is a non-steroidal anti-inflammatory drug.

Technology Process of 2-amino-3-benzoyl-α-(1-propylthio)-benzeneacetamide

There total 1 articles about 2-amino-3-benzoyl-α-(1-propylthio)-benzeneacetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

tert-butylhypochlorite (507-40-4) + 2-(1-Propylthio)acetamide (78281-83-1) + (2-aminophenyl)(phenyl)methanone (2835-77-0) → 1,2-amino-3-benzoyl-α-(n-propylthiophenylacetamide + 2-amino-3-benzoyl-α-(1-propylthio)-benzeneacetamide (173262-94-7)

Guidance literature:

Reference yield:

2-amino-3-benzoyl-α-(1-propylthio)-benzeneacetamide (173262-94-7) → nepafenac (78281-72-8)

Guidance literature:

upstream raw materials:

tert-butylhypochlorite

2-(1-Propylthio)acetamide

(2-aminophenyl)(phenyl)methanone

Downstream raw materials:

nepafenac

Refernces