Technology Process of C29H18F4N6O
There total 10 articles about C29H18F4N6O which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
isopropylamine;
In
ethanol; n-heptane;
Resolution of racemate;
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: TurboGrignard / tetrahydrofuran / 1 h / Inert atmosphere
1.2: 22 h / 20 °C / Inert atmosphere
2.1: n-butyllithium / tetrahydrofuran; hexane / 0.02 h / -78 °C / Inert atmosphere
2.2: 1.17 h / -78 °C / Inert atmosphere
2.3: Inert atmosphere
3.1: tris-(dibenzylideneacetone)dipalladium(0); zinc; XPhos / N,N-dimethyl acetamide / 4.5 h / 120 °C / Inert atmosphere
4.1: isopropylamine / ethanol; n-heptane / Resolution of racemate
With
tris-(dibenzylideneacetone)dipalladium(0); TurboGrignard; n-butyllithium; isopropylamine; zinc; XPhos;
In
tetrahydrofuran; ethanol; hexane; n-heptane; N,N-dimethyl acetamide;
- Guidance literature:
-
Multi-step reaction with 6 steps
1.1: oxalyl dichloride / dichloromethane; N,N-dimethyl-formamide / 20 °C / Inert atmosphere
2.1: diisopropylamine / dichloromethane; water / 7 - 20 °C / Inert atmosphere
3.1: TurboGrignard / tetrahydrofuran / 1 h / Inert atmosphere
3.2: 22 h / 20 °C / Inert atmosphere
4.1: n-butyllithium / tetrahydrofuran; hexane / 0.02 h / -78 °C / Inert atmosphere
4.2: 1.17 h / -78 °C / Inert atmosphere
4.3: Inert atmosphere
5.1: tris-(dibenzylideneacetone)dipalladium(0); zinc; XPhos / N,N-dimethyl acetamide / 4.5 h / 120 °C / Inert atmosphere
6.1: isopropylamine / ethanol; n-heptane / Resolution of racemate
With
tris-(dibenzylideneacetone)dipalladium(0); TurboGrignard; n-butyllithium; oxalyl dichloride; isopropylamine; diisopropylamine; zinc; XPhos;
In
tetrahydrofuran; ethanol; hexane; n-heptane; dichloromethane; N,N-dimethyl acetamide; water; N,N-dimethyl-formamide;