3,4,5,7-tetra-O-benzyl-1-deoxy-1-[2-(1-(2,2,2-trichloroethoxy)carbonyl)benzimidazolyl]-α-D-gluco-2-heptulopyranose

Base Information

Chemical Name:3,4,5,7-tetra-O-benzyl-1-deoxy-1-[2-(1-(2,2,2-trichloroethoxy)carbonyl)benzimidazolyl]-α-D-gluco-2-heptulopyranose
CAS No.:191097-72-0
Molecular Formula:C₄₅H₄₃Cl₃N₂O₈
Molecular Weight:846.204
Hs Code.:

Synonyms:3,4,5,7-tetra-O-benzyl-1-deoxy-1-[2-(1-(2,2,2-trichloroethoxy)carbonyl)benzimidazolyl]-α-D-gluco-2-heptulopyranose

Suppliers and Price of 3,4,5,7-tetra-O-benzyl-1-deoxy-1-[2-(1-(2,2,2-trichloroethoxy)carbonyl)benzimidazolyl]-α-D-gluco-2-heptulopyranose

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 3,4,5,7-tetra-O-benzyl-1-deoxy-1-[2-(1-(2,2,2-trichloroethoxy)carbonyl)benzimidazolyl]-α-D-gluco-2-heptulopyranose

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 3,4,5,7-tetra-O-benzyl-1-deoxy-1-[2-(1-(2,2,2-trichloroethoxy)carbonyl)benzimidazolyl]-α-D-gluco-2-heptulopyranose

There total 3 articles about 3,4,5,7-tetra-O-benzyl-1-deoxy-1-[2-(1-(2,2,2-trichloroethoxy)carbonyl)benzimidazolyl]-α-D-gluco-2-heptulopyranose which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 45.0%

: 191097-59-3
1-(2-benzimidazolyl)-3,4,5,7-tetra-O-benzyl-1-deoxy-α-D-gluco-2-heptulopyranose

: 17341-93-4
2,2,2-Trichloroethyl chloroformate

: 191097-72-0
3,4,5,7-tetra-O-benzyl-1-deoxy-1-[2-(1-(2,2,2-trichloroethoxy)carbonyl)benzimidazolyl]-α-D-gluco-2-heptulopyranose

Guidance literature:: With triethylamine; In dichloromethane; at -20 ℃; for 0.333333h;
DOI:10.1080/07328309708006530

Reference yield:

: 13096-62-3
(3R,4S,5R,6R)-3,4,5-tris(benzyloxy)-6-((benzyloxy)methyl)tetrahydro-2H-pyran-2-one

: 191097-72-0
3,4,5,7-tetra-O-benzyl-1-deoxy-1-[2-(1-(2,2,2-trichloroethoxy)carbonyl)benzimidazolyl]-α-D-gluco-2-heptulopyranose

Guidance literature:: Multi-step reaction with 2 steps

1.1: n-butyllithium / tetrahydrofuran; hexane / 1 h

1.2: 76 percent / tetrahydrofuran; hexane / 1 h / -85 °C

2.1: 45 percent / triethylamine / CH₂Cl₂ / 0.33 h / -20 °C

With n-butyllithium; triethylamine; In tetrahydrofuran; hexane; dichloromethane; 1.1: Metallation / 1.2: Addition / 2.1: alkoxycarbonylation;
DOI:10.1080/07328309708006530

Reference yield:

: 615-15-6
2-Methyl-1H-benzimidazole

: 191097-72-0
3,4,5,7-tetra-O-benzyl-1-deoxy-1-[2-(1-(2,2,2-trichloroethoxy)carbonyl)benzimidazolyl]-α-D-gluco-2-heptulopyranose

Guidance literature:: Multi-step reaction with 2 steps

1.1: n-butyllithium / tetrahydrofuran; hexane / 1 h

1.2: 76 percent / tetrahydrofuran; hexane / 1 h / -85 °C

2.1: 45 percent / triethylamine / CH₂Cl₂ / 0.33 h / -20 °C

With n-butyllithium; triethylamine; In tetrahydrofuran; hexane; dichloromethane; 1.1: Metallation / 1.2: Addition / 2.1: alkoxycarbonylation;
DOI:10.1080/07328309708006530