N-(3,4-Dimethylphenyl)-2-(hydroxyimino)acetamide

Base Information

• Chemical Name: N-(3,4-Dimethylphenyl)-2-(hydroxyimino)acetamide
• CAS No.: 17122-69-9
• Molecular Formula: C10H12 N2 O2
• Molecular Weight: 192.217
• NSC Number: 106587
• Mol file: 17122-69-9.mol

Synonyms:N-(3,4-DIMETHYLPHENYL)-2-(HYDROXYIMINO)ACETAMIDE;17122-69-9;(2E)-N-(3,4-dimethylphenyl)-2-hydroxyiminoacetamide;NSC106587;SCHEMBL21949121;AKOS024325084;NSC-106587;2-(HYDROXYIMINO)-3',4'-DIMETHYLACETANILIDE

Chemical Property of N-(3,4-Dimethylphenyl)-2-(hydroxyimino)acetamide

Chemical Property:

• Boiling Point: °Cat760mmHg
• Flash Point: °C
• PSA: 61.69000
• Density: 1.14g/cm³
• LogP: 1.77490
• XLogP3: 2.8
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 2
• Exact Mass: 192.089877630
• Heavy Atom Count: 14
• Complexity: 228

Purity/Quality:

98%min ^*data from raw suppliers

2-(HYDROXYIMINO)-3',4'-DIMETHYLACETANILIDE Aldrich ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=C(C=C(C=C1)NC(=O)C=NO)C
• Isomeric SMILES: CC1=C(C=C(C=C1)NC(=O)/C=N/O)C

Technology Process of N-(3,4-Dimethylphenyl)-2-(hydroxyimino)acetamide

There total 4 articles about N-(3,4-Dimethylphenyl)-2-(hydroxyimino)acetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

chloral (75-87-6) + 4-amino-o-xylene (95-64-7) → hydroxyimino-acetic acid-(3,4-dimethyl-anilide) (17122-69-9)

Guidance literature:

With hydrogenchloride; hydroxylamine; sodium sulfate; In water; for 1h; Heating / reflux;

Reference yield:

chloral hydrate (302-17-0) + 4-amino-o-xylene (95-64-7) → hydroxyimino-acetic acid-(3,4-dimethyl-anilide) (17122-69-9)

Guidance literature:

With hydrogenchloride; hydroxylamine; sodium sulfate;

DOI:10.1021/jo01135a015

Reference yield:

chloral hydrate (302-17-0) + 3,4-dimethylaniline hydrochloride (7356-54-9) → hydroxyimino-acetic acid-(3,4-dimethyl-anilide) (17122-69-9)

Guidance literature:

With hydroxylamine hydrochloride; water; sodium sulfate;

upstream raw materials:

chloral hydrate

3,4-dimethylaniline hydrochloride

4-amino-o-xylene

chloral

Downstream raw materials:

1,3-bis(3,4-dimethylphenyl)urea

4,5-dimethylanthranilic acid

6,7-dimethyl-quinoline-4-carboxylic acid