1-menthoxyethylmethane sulfonate

Base Information

• Chemical Name: 1-menthoxyethylmethane sulfonate
• CAS No.: 870719-65-6
• Molecular Formula: C₁₃H₂₆O₄S
• Molecular Weight: 278.413
• Mol file: 870719-65-6.mol

Synonyms:1-menthoxyethylmethane sulfonate

Chemical Property of 1-menthoxyethylmethane sulfonate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1-menthoxyethylmethane sulfonate

There total 2 articles about 1-menthoxyethylmethane sulfonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.2%

2-(L-menthoxy)ethanol (7378-38-3,38618-23-4,75443-64-0) + methanesulfonyl chloride (124-63-0) → 1-menthoxyethylmethane sulfonate (870719-65-6)

Guidance literature:

With triethylamine; In toluene; at 1 - 10 ℃; for 1h;

Reference yield:

(-)-menthol (2216-51-5) → 1-menthoxyethylmethane sulfonate (870719-65-6)

Guidance literature:

Multi-step reaction with 2 steps

1: aluminum (III) chloride / toluene / 1 h / 5 - 20 °C

2: triethylamine / toluene / 1 h / 1 - 10 °C

With aluminum (III) chloride; triethylamine; In toluene;

Reference yield: 88.0%

1-menthoxyethylmethane sulfonate (870719-65-6) → diethylene glycol monomenthyl ether

Guidance literature:

ethylene glycol; With sodium hydride; In DMF (N,N-dimethyl-formamide); at 0 - 20 ℃; for 1h;

1-menthoxyethylmethane sulfonate; In DMF (N,N-dimethyl-formamide); at 70 - 74 ℃; for 3.83333h; Product distribution / selectivity;

upstream raw materials:

2-(L-menthoxy)ethanol

methanesulfonyl chloride

(-)-menthol