1-(1-(4-methoxyphenyl)-2,5-dimethyl-4-phenyl-1H-pyrrol-3-yl)ethanone

Base Information

• Chemical Name: 1-(1-(4-methoxyphenyl)-2,5-dimethyl-4-phenyl-1H-pyrrol-3-yl)ethanone
• CAS No.: 1600521-19-4
• Molecular Formula: C₂₁H₂₁NO₂
• Molecular Weight: 319.403
• Mol file: 1600521-19-4.mol

Synonyms:1-(1-(4-methoxyphenyl)-2,5-dimethyl-4-phenyl-1H-pyrrol-3-yl)ethanone

Chemical Property of 1-(1-(4-methoxyphenyl)-2,5-dimethyl-4-phenyl-1H-pyrrol-3-yl)ethanone

Chemical Property:

Purity/Quality:

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Technology Process of 1-(1-(4-methoxyphenyl)-2,5-dimethyl-4-phenyl-1H-pyrrol-3-yl)ethanone

There total 2 articles about 1-(1-(4-methoxyphenyl)-2,5-dimethyl-4-phenyl-1H-pyrrol-3-yl)ethanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

1-phenyl-2-nitroprop-1-ene (705-60-2,18315-84-9,58321-79-2) + 4-methoxy-aniline (104-94-9) + acetylacetone (123-54-6,81235-32-7) → 1-(1-(4-methoxyphenyl)-2,5-dimethyl-4-phenyl-1H-pyrrol-3-yl)ethanone (1600521-19-4)

Guidance literature:

With nano CoFe₂O₄ supported on SiO₂-DABCO-Sb; In ethanol; at 80 ℃; for 12h; Green chemistry;

DOI:10.1039/c3ra47855f

Reference yield: 78.0%

Nitroethane (79-24-3) + benzaldehyde (100-52-7) + 4-methoxy-aniline (104-94-9) + acetylacetone (123-54-6,81235-32-7) → 1-(1-(4-methoxyphenyl)-2,5-dimethyl-4-phenyl-1H-pyrrol-3-yl)ethanone (1600521-19-4)

Guidance literature:

With Fe(III)-Schiff base complex supported on Santa Barbara Amorphous-15; Reflux; Green chemistry;

DOI:10.1080/24701556.2020.1744650

upstream raw materials:

1-phenyl-2-nitroprop-1-ene

4-methoxy-aniline

acetylacetone

Nitroethane