3-(1,3-dioxolan-2-yl)prop-1-yl[2-(2-hydroxyprop-2-yl)phenyl]diisopropylsilane

Base Information

• Chemical Name: 3-(1,3-dioxolan-2-yl)prop-1-yl[2-(2-hydroxyprop-2-yl)phenyl]diisopropylsilane
• CAS No.: 1239384-20-3
• Molecular Formula: C₂₁H₃₆O₃Si
• Molecular Weight: 364.601
• Mol file: 1239384-20-3.mol

Synonyms:3-(1,3-dioxolan-2-yl)prop-1-yl[2-(2-hydroxyprop-2-yl)phenyl]diisopropylsilane

Chemical Property of 3-(1,3-dioxolan-2-yl)prop-1-yl[2-(2-hydroxyprop-2-yl)phenyl]diisopropylsilane

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3-(1,3-dioxolan-2-yl)prop-1-yl[2-(2-hydroxyprop-2-yl)phenyl]diisopropylsilane

There total 1 articles about 3-(1,3-dioxolan-2-yl)prop-1-yl[2-(2-hydroxyprop-2-yl)phenyl]diisopropylsilane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

4-oxo-but-1-yl[2-(2-hydroxyprop-2-yl)phenyl]diisopropylsilane (1239384-19-0) + ethylene glycol (107-21-1) → 3-(1,3-dioxolan-2-yl)prop-1-yl[2-(2-hydroxyprop-2-yl)phenyl]diisopropylsilane (1239384-20-3)

Guidance literature:

With pyridinium p-toluenesulfonate; In benzene; for 3h; Reflux;

DOI:10.1002/anie.201000816

Reference yield: 84.0%

4-bromobenzenecarbonitrile (623-00-7) + 3-(1,3-dioxolan-2-yl)prop-1-yl[2-(2-hydroxyprop-2-yl)phenyl]diisopropylsilane (1239384-20-3) → 3,3-dimethyl-1,1-diisopropyl-1,3-dihydrobenzo[c][1,2]oxasilole (1239384-09-8) + 4-[3-(1,3-dioxolan-2-yl)prop-1-yl]benzonitrile (101478-65-3)

Guidance literature:

With 1,1'-bis-(diphenylphosphino)ferrocene; potassium phosphate; bis(1,1,1,5,5,5-hexafluoropentane-2,4-dionato)copper(II) monohydrate; palladium diacetate; In tetrahydrofuran; at 100 ℃; for 1h; Inert atmosphere;

DOI:10.1002/anie.201000816

upstream raw materials:

4-oxo-but-1-yl[2-(2-hydroxyprop-2-yl)phenyl]diisopropylsilane

ethylene glycol

Downstream raw materials:

3,3-dimethyl-1,1-diisopropyl-1,3-dihydrobenzo[c][1,2]oxasilole

4-[3-(1,3-dioxolan-2-yl)prop-1-yl]benzonitrile