1-(2-Chlorophenyl)-2-methylpropan-2-ol

Base Information

Chemical Name:1-(2-Chlorophenyl)-2-methylpropan-2-ol
CAS No.:6256-31-1
Molecular Formula:C10H13 Cl O
Molecular Weight:184.666
Hs Code.:2906299090
European Community (EC) Number:228-386-8
NSC Number:7112
UNII:U5E3W6TJ82
DSSTox Substance ID:DTXSID1064168
Nikkaji Number:J211.479H
Wikidata:Q81991303
Mol file:6256-31-1.mol

Synonyms:1-(2-chlorophenyl)-2-methylpropan-2-ol;6256-31-1;o-Chlorobenzyldimethylcarbinol;1-(2-chlorophenyl)-2-methyl-2-propanol;o-Chloro-alpha,alpha-dimethylphenethyl alcohol;Benzeneethanol, 2-chloro-alpha,alpha-dimethyl-;NSC 7112;NSC-7112;Benzeneethanol, 2-chloro-.alpha.,.alpha.-dimethyl-;EINECS 228-386-8;MFCD11610689;2-Chloro-alpha,alpha-dimethylbenzeneethanol;NSC7112;U5E3W6TJ82;DTXSID1064168;AKOS010014942;Benzeneethanol,2-chloro-a,a-dimethyl-;AS-50807;SY035186;1-(2-chlorophenyl)-2-methyl-propan-2-ol;CS-0054176;FT-0754201;EN300-68196;P11161;A834908;A868437;Phenethyl alcohol, o-chloro-alpha,alpha-dimethyl-;Phenethyl alcohol, o-chloro-.alpha.,.alpha.-dimethyl-;Z513707752

Suppliers and Price of 1-(2-Chlorophenyl)-2-methylpropan-2-ol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
1-(2-CHLOROPHENYL)-2-METHYLPROPAN-2-OL 95+%
5g
$ 719.00

Chemenu
1-(2-chlorophenyl)-2-methylpropan-2-ol 95%
5g
$ 679.00

American Custom Chemicals Corporation
1-(2-CHLOROPHENYL)-2-METHYLPROPAN-2-OL 95.00%
5G
$ 1548.26

American Custom Chemicals Corporation
1-(2-CHLOROPHENYL)-2-METHYLPROPAN-2-OL 95.00%
2.5G
$ 1227.82

American Custom Chemicals Corporation
1-(2-CHLOROPHENYL)-2-METHYLPROPAN-2-OL 95.00%
1G
$ 852.55

Alichem
1-(2-Chlorophenyl)-2-methylpropan-2-ol
5g
$ 726.00

Total 13 raw suppliers

Chemical Property of 1-(2-Chlorophenyl)-2-methylpropan-2-ol

Chemical Property:

Boiling Point:110 °C(Press: 3 Torr)
PKA:14.85±0.29(Predicted)
Flash Point:113oC
PSA：20.23000
Density:1.120±0.06 g/cm3(Predicted)
LogP:2.65340
Storage Temp.:Sealed in dry,Room Temperature
XLogP3:2.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:2
Exact Mass:184.0654927
Heavy Atom Count:12
Complexity:145

Purity/Quality:

97% ^*data from raw suppliers

1-(2-CHLOROPHENYL)-2-METHYLPROPAN-2-OL 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(CC1=CC=CC=C1Cl)O

Technology Process of 1-(2-Chlorophenyl)-2-methylpropan-2-ol

There total 2 articles about 1-(2-Chlorophenyl)-2-methylpropan-2-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 6305-95-9
2-chlorophenylacetone

: 75-16-1
methylmagnesium bromide

: 6256-31-1
o-chloro-α,α-dimethylphenethyl alcohol

Guidance literature:: In diethyl ether; Reflux; Inert atmosphere;
DOI:10.1021/ja101909t

Reference yield:

: 611-19-8
1-chloro-2-(chloromethyl)benzene

: 67-64-1
acetone

: 6256-31-1
o-chloro-α,α-dimethylphenethyl alcohol

Guidance literature:: Multistep reaction; (i) Mg, Et₂O, (ii) /BRN= 635680/;

Reference yield:

: 6256-31-1
o-chloro-α,α-dimethylphenethyl alcohol

: ((S)-1-Formyl-pentyl)-carbamic acid 2-(2-chloro-phenyl)-1,1-dimethyl-ethyl ester

Guidance literature:: Multi-step reaction with 5 steps

1: toluene / 90 °C

2: aq. LiOH / tetrahydrofuran

3: Et₃N / tetrahydrofuran / -10 °C

4: NaBH₄ / tetrahydrofuran; H₂O / 0 °C

5: 77 percent / pyridine*SO₃; DMSO; Et₃N / CH₂Cl₂ / -10 °C

With lithium hydroxide; sodium tetrahydroborate; sulfur trioxide pyridine complex; dimethyl sulfoxide; triethylamine; In tetrahydrofuran; dichloromethane; water; toluene; 5: Moffat oxidation;
DOI:10.1016/j.bmcl.2004.04.084