8-FLUOROADENOSINE

Base Information

Chemical Name:8-FLUOROADENOSINE
CAS No.:23205-67-6
Molecular Formula:C₁₀H₁₂FN₅O₄
Molecular Weight:285.235
Hs Code.:
Mol file:23205-67-6.mol

Synonyms:8-Fluoroadenosine;NSC 341925

Suppliers and Price of 8-FLUOROADENOSINE

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
8-FLUOROADENOSINE 98.00%
5G
$ 2102.10

Total 10 raw suppliers

Chemical Property of 8-FLUOROADENOSINE

Chemical Property:

Vapor Pressure:2.32E-20mmHg at 25°C
Boiling Point:696.5°Cat760mmHg
PKA:12.88±0.70(Predicted)
Flash Point:375°C
PSA：139.54000
Density:2.17g/cm³
LogP:-1.25970

Purity/Quality:

97% ^*data from raw suppliers

8-FLUOROADENOSINE 98.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Uses The first non-enzymic synthesis of 8-Fluoroadenosine was described. The intermediate generation of 8-?fluoroadenosines as a tool to increase the reaction rates of nucleophilic substitutions was briefly examined.

Technology Process of 8-FLUOROADENOSINE

There total 10 articles about 8-FLUOROADENOSINE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 46.0%

: 938053-00-0
8-fluoro-2',3'-O-(1-methylethylidene)adenosine

: 23205-67-6
8-fluoroadenosine

: 19325-87-2,19325-89-4,29851-57-8
8-oxoadenosine

Guidance literature:: With perchloric acid; In water; at 20 ℃; for 1h;
DOI:10.1016/j.tet.2007.02.053

Reference yield: 44.9%

: 23205-66-5
O^2'_,O3'_,O5'5'-triacetyl-8-fluoro-adenosine

: 23205-67-6
8-fluoroadenosine

Guidance literature:: With ESL-001-02 biocatalyst; In methanol; at 45 ℃; for 3h;
DOI:10.1016/S0040-4039(98)01594-9

Reference yield:

: 104354-34-9
8-bromo-2',3'-O-(1-methylethylidene)-5'-O-(tetrahydro-2H-pyran-2-yl)adenosine

: 23205-67-6
8-fluoroadenosine

Guidance literature:: Multi-step reaction with 3 steps

1: 28 percent / cesium fluoride / acetonitrile / 12 h / 100 °C

2: 63 percent / trifluoroacetic acid / acetonitrile / 0.75 h / 20 °C

3: 46 percent / perchloric acid / H₂O / 1 h / 20 °C

With perchloric acid; cesium fluoride; trifluoroacetic acid; In water; acetonitrile;
DOI:10.1016/j.tet.2007.02.053