(2S)-ethyl 2-(((4-nitrophenoxy)(phenoxy)phosphoryl)amino)-3-phenylpropanoate

Base Information

Chemical Name:(2S)-ethyl 2-(((4-nitrophenoxy)(phenoxy)phosphoryl)amino)-3-phenylpropanoate
CAS No.:1273029-33-6
Molecular Formula:C₂₃H₂₃N₂O₇P
Molecular Weight:470.419
Hs Code.:

Synonyms:(2S)-ethyl 2-(((4-nitrophenoxy)(phenoxy)phosphoryl)amino)-3-phenylpropanoate

Suppliers and Price of (2S)-ethyl 2-(((4-nitrophenoxy)(phenoxy)phosphoryl)amino)-3-phenylpropanoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 1 raw suppliers

Chemical Property of (2S)-ethyl 2-(((4-nitrophenoxy)(phenoxy)phosphoryl)amino)-3-phenylpropanoate

Chemical Property:

Purity/Quality:: 98% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

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Technology Process of (2S)-ethyl 2-(((4-nitrophenoxy)(phenoxy)phosphoryl)amino)-3-phenylpropanoate

There total 3 articles about (2S)-ethyl 2-(((4-nitrophenoxy)(phenoxy)phosphoryl)amino)-3-phenylpropanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 60.0%

: 100-02-7,78813-13-5,89830-32-0
4-nitro-phenol

: 3182-93-2
(L)-phenylalanine ethyl ester hydrochloride

: 770-12-7
O-phenyl phosphorodichloridate

: 1273029-33-6
(2S)-ethyl 2-(((4-nitrophenoxy)(phenoxy)phosphoryl)amino)-3-phenylpropanoate

Guidance literature:: (L)-phenylalanine ethyl ester hydrochloride; O-phenyl phosphorodichloridate; With triethylamine; In dichloromethane; at 0 - 20 ℃; for 1.41667h;

4-nitro-phenol; With triethylamine; In dichloromethane;
DOI:10.1021/acs.jmedchem.6b01594

Reference yield:

: 63-91-2,25191-15-5,658-69-5,67675-33-6
L-phenylalanine

: 1273029-33-6
(2S)-ethyl 2-(((4-nitrophenoxy)(phenoxy)phosphoryl)amino)-3-phenylpropanoate

Guidance literature:: Multi-step reaction with 2 steps

1: chloro-trimethyl-silane / 80 °C

2: triethylamine / dichloromethane / 1.33 h / 0 - 20 °C

With chloro-trimethyl-silane; triethylamine; In dichloromethane;