(E)-3-((S)-2,2,4-Trimethyl-cyclohex-3-enylmethoxy)-acrylic acid methyl ester

Base Information

• Chemical Name: (E)-3-((S)-2,2,4-Trimethyl-cyclohex-3-enylmethoxy)-acrylic acid methyl ester
• CAS No.: 326907-23-7
• Molecular Formula: C₁₄H₂₂O₃
• Molecular Weight: 238.327
• Mol file: 326907-23-7.mol

Synonyms:(E)-3-((S)-2,2,4-Trimethyl-cyclohex-3-enylmethoxy)-acrylic acid methyl ester

Chemical Property of (E)-3-((S)-2,2,4-Trimethyl-cyclohex-3-enylmethoxy)-acrylic acid methyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (E)-3-((S)-2,2,4-Trimethyl-cyclohex-3-enylmethoxy)-acrylic acid methyl ester

There total 5 articles about (E)-3-((S)-2,2,4-Trimethyl-cyclohex-3-enylmethoxy)-acrylic acid methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

propynoic acid methyl ester (922-67-8) + (-)-(S)-2,2,4-trimethyl-3-cyclohexene-1-methanol (108448-46-0) → (E)-3-((S)-2,2,4-Trimethyl-cyclohex-3-enylmethoxy)-acrylic acid methyl ester (326907-23-7)

Guidance literature:

With 4-methyl-morpholine; In diethyl ether;

DOI:10.1016/S0957-4166(00)00345-1

Reference yield:

(2,2,4-trimethyl-3-cyclohexen-1-yl)methanol (55695-33-5) → (E)-3-((S)-2,2,4-Trimethyl-cyclohex-3-enylmethoxy)-acrylic acid methyl ester (326907-23-7)

Guidance literature:

Multi-step reaction with 3 steps

1: PPL (SIGMA type II) from Porcine pancreas / diisopropyl ether; hexane / 72 h / 20 °C

2: 57 percent / PPL (SIGMA type II) from Porcine pancreas / toluene / 48 h / 20 °C / pH 7

3: 100 percent / N-methylmorpholine / diethyl ether

With 4-methyl-morpholine; PPL (SIGMA type II) from Porcine pancreas; In diethyl ether; hexane; di-isopropyl ether; toluene;

DOI:10.1016/S0957-4166(00)00345-1

Reference yield:

acetic acid-(2,2,4-trimethyl-cyclohex-3-enylmethyl ester) (127075-63-2) → (E)-3-((S)-2,2,4-Trimethyl-cyclohex-3-enylmethoxy)-acrylic acid methyl ester (326907-23-7)

Guidance literature:

Multi-step reaction with 2 steps

1: PPL (SIGMA type II) from Porcine pancreas / toluene / 48 h / 20 °C / pH 7

2: 100 percent / N-methylmorpholine / diethyl ether

With 4-methyl-morpholine; PPL (SIGMA type II) from Porcine pancreas; In diethyl ether; toluene;

DOI:10.1016/S0957-4166(00)00345-1

upstream raw materials:

propynoic acid methyl ester

(-)-(S)-2,2,4-trimethyl-3-cyclohexene-1-methanol

(2,2,4-trimethyl-3-cyclohexen-1-yl)methanol

acetic acid-(2,2,4-trimethyl-cyclohex-3-enylmethyl ester)

Downstream raw materials:

(E)-3-((1R,3S)-3-Hydroxymethyl-2,2-dimethyl-6-methylene-cyclohexyl)-acrylic acid

(E)-3-((1R,5S)-5-Hydroxymethyl-2,6,6-trimethyl-cyclohex-2-enyl)-acrylic acid

(E)-3-((1R,3S)-2,2,3-Trimethyl-6-methylene-cyclohexyl)-acrylic acid

(E)-3-((1R,5S)-2,5,6,6-Tetramethyl-cyclohex-2-enyl)-acrylic acid