p-Methoxybenzyl p-anisate

Base Information

• Chemical Name: p-Methoxybenzyl p-anisate
• CAS No.: 24318-43-2
• Molecular Formula: C16H16 O4
• Molecular Weight: 272.301
• Hs Code.: 2918990090
• European Community (EC) Number: 246-159-1
• NSC Number: 78835
• UNII: MH827WPN5X
• DSSTox Substance ID: DTXSID20179060
• Nikkaji Number: J287.209I
• Wikidata: Q83049586
• Mol file: 24318-43-2.mol

Synonyms:p-Methoxybenzyl p-anisate;24318-43-2;(4-methoxyphenyl)methyl 4-methoxybenzoate;MH827WPN5X;EINECS 246-159-1;NSC-78835;AI3-18958;Benzoic acid, 4-methoxy-, (4-methoxyphenyl)methyl ester;4-methoxybenzyl 4-methoxybenzoate;NSC78835;UNII-MH827WPN5X;NCIOpen2_004331;SCHEMBL16689961;DTXSID20179060;NSC 78835;AKOS008732230;4-Methoxybenzoic acid 4-methoxybenzyl ester;P-ANISIC ACID, P-METHOXYBENZYL ESTER;BENZYL ALCOHOL, P-METHOXY-, P-ANISATE

Chemical Property of p-Methoxybenzyl p-anisate

Chemical Property:

• Vapor Pressure: 4.89E-07mmHg at 25°C
• Boiling Point: 413.2°C at 760 mmHg
• Flash Point: 183.1°C
• PSA: 44.76000
• Density: 1.153g/cm³
• LogP: 3.06080
• XLogP3: 3.9
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 6
• Exact Mass: 272.10485899
• Heavy Atom Count: 20
• Complexity: 289

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COC1=CC=C(C=C1)COC(=O)C2=CC=C(C=C2)OC

Technology Process of p-Methoxybenzyl p-anisate

There total 43 articles about p-Methoxybenzyl p-anisate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

p-methylanizole (104-93-8) → 4-methoxybenzyl 4-methoxybenzoate (24318-43-2)

Guidance literature:

With tert.-butylhydroperoxide; tetra-(n-butyl)ammonium iodide; In water; at 80 ℃; for 6h;

DOI:10.1039/c3cc40832a

Reference yield: 97.0%

4-methoxy-benzaldehyde (123-11-5) → 4-methoxybenzyl 4-methoxybenzoate (24318-43-2)

Guidance literature:

With sodium hydride; for 16h; Neat (no solvent); High speed ball milling;

DOI:10.1039/b810714a

Reference yield: 97.0%

p-methylanizole (104-93-8) + 4-methoxybenzoic acid (100-09-4) → 4-methoxybenzyl 4-methoxybenzoate (24318-43-2)

Guidance literature:

With tert.-butylhydroperoxide; choline chloride; tetra-(n-butyl)ammonium iodide; urea; In water; at 80 ℃; for 12h; Green chemistry;

DOI:10.1007/s13738-020-02039-1

upstream raw materials:

4-methoxy-benzaldehyde

4-methoxy-benzoyl chloride

4-Methoxybenzyl alcohol

4-methoxybenzoic acid

Downstream raw materials:

4-methoxybenzoic acid

5-[(4-methoxybenzyl)sulfanyl]-1-phenyl-1H-tetrazole

Refernces

• 1、 Mukherjee, Aparajita,Bhattacharya, Samaresh. "Dual utility of a single diphosphine-ruthenium complex: A precursor for new complexes and, a pre-catalyst for transfer-hydrogenation and Oppenauer oxidation". . p. 15617 - 15631. Retrieved 2021/05/19.
• 2、 Moayyed, Mohammadesmaeil,Saberi, Dariush. "Iodine-catalyzed synthesis of β-uramino crotonic esters as well as oxidative esterification of carboxylic acids in choline chloride/urea: a desirable alternative to organic solvents". . p. 445 - 455. Retrieved 2020/09/07.