(6-chloro-1-methyl-1H-imidazo[4,5-c]pyridin-4-yl)-(2,4-dimethoxybenzyl)amine

Base Information

• Chemical Name: (6-chloro-1-methyl-1H-imidazo[4,5-c]pyridin-4-yl)-(2,4-dimethoxybenzyl)amine
• CAS No.: 1271024-42-0
• Molecular Formula: C₁₆H₁₇ClN₄O₂
• Molecular Weight: 332.79
• Mol file: 1271024-42-0.mol

Synonyms:(6-chloro-1-methyl-1H-imidazo[4,5-c]pyridin-4-yl)-(2,4-dimethoxybenzyl)amine

Chemical Property of (6-chloro-1-methyl-1H-imidazo[4,5-c]pyridin-4-yl)-(2,4-dimethoxybenzyl)amine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (6-chloro-1-methyl-1H-imidazo[4,5-c]pyridin-4-yl)-(2,4-dimethoxybenzyl)amine

There total 1 articles about (6-chloro-1-methyl-1H-imidazo[4,5-c]pyridin-4-yl)-(2,4-dimethoxybenzyl)amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

4,6-dichloro-1-methyl-1H-imidazo [4,5-c]pyridine (887147-19-5) + 2,4-Dimethoxybenzylamine (20781-20-8) → (6-chloro-1-methyl-1H-imidazo[4,5-c]pyridin-4-yl)-(2,4-dimethoxybenzyl)amine (1271024-42-0)

Guidance literature:

at 110 ℃; for 3h;

Reference yield: 78.0%

di-tert-butyl dicarbonate (24424-99-5) + (6-chloro-1-methyl-1H-imidazo[4,5-c]pyridin-4-yl)-(2,4-dimethoxybenzyl)amine (1271024-42-0) → tert-butyl 6-chloro-1-methyl-1H-imidazo[4.5-c]pyridin-4-yl(2,4-dimethoxybenzyl)carbamate (1271024-44-2)

Guidance literature:

(6-chloro-1-methyl-1H-imidazo[4,5-c]pyridin-4-yl)-(2,4-dimethoxybenzyl)amine; With sodium hexamethyldisilazane; In tetrahydrofuran; at -78 ℃;

di-tert-butyl dicarbonate; In tetrahydrofuran; at -78 - 20 ℃;

Reference yield:

(6-chloro-1-methyl-1H-imidazo[4,5-c]pyridin-4-yl)-(2,4-dimethoxybenzyl)amine (1271024-42-0) + acetyl chloride (75-36-5) → C18H19ClN4O3

Guidance literature:

With pyridine; In dichloromethane; at 20 ℃;

upstream raw materials:

4,6-dichloro-1-methyl-1H-imidazo [4,5-c]pyridine

2,4-Dimethoxybenzylamine

Downstream raw materials:

tert-butyl 6-chloro-1-methyl-1H-imidazo[4.5-c]pyridin-4-yl(2,4-dimethoxybenzyl)carbamate

tert-butyl 6-amino-1-methyl-1H-imidazo[4,5-c]pyridin-4-yl(2,4-dimethoxybenzyl)carbamate

BMS-911543

tert-butyl 6-amino-7-iodo-1-methyl-1H-imidazo[4,5-c]pyridin-4-yl(2,4-dimethoxybenzyl)carbamate