isopropyl (2R,3S)-2-benzyloxy-4-cyclohexyl-3-<(S)-(1-phenylethyl)amino>butyrate

Base Information

• Chemical Name: isopropyl (2R,3S)-2-benzyloxy-4-cyclohexyl-3-<(S)-(1-phenylethyl)amino>butyrate
• CAS No.: 129397-43-9
• Molecular Formula: C₂₈H₃₉NO₃
• Molecular Weight: 437.623
• Mol file: 129397-43-9.mol

Synonyms:isopropyl (2R,3S)-2-benzyloxy-4-cyclohexyl-3-<(S)-(1-phenylethyl)amino>butyrate

Chemical Property of isopropyl (2R,3S)-2-benzyloxy-4-cyclohexyl-3-<(S)-(1-phenylethyl)amino>butyrate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of isopropyl (2R,3S)-2-benzyloxy-4-cyclohexyl-3-<(S)-(1-phenylethyl)amino>butyrate

There total 1 articles about isopropyl (2R,3S)-2-benzyloxy-4-cyclohexyl-3-<(S)-(1-phenylethyl)amino>butyrate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3-benzyloxy-4-cyclohexylmethyl-1-<(S)-1-phenylethyl>-2-azetidinone (129397-39-3,129446-09-9,129446-10-2,129446-11-3) + isopropyl alcohol (67-63-0,8013-70-5) → isopropyl (2R,3S)-2-benzyloxy-4-cyclohexyl-3-<(S)-(1-phenylethyl)amino>butyrate (129397-43-9)

Guidance literature:

With hydrogenchloride; at 0 - 20 ℃; Yield given;

Reference yield: 99.0%

isopropyl (2R,3S)-2-benzyloxy-4-cyclohexyl-3-<(S)-(1-phenylethyl)amino>butyrate (129397-43-9) → 2(R)-hydroxy-3(S)-amino-4-cyclohexylbutanoic acid 2-propyl ester (119642-26-1)

Guidance literature:

With hydrogen; palladium on activated charcoal; In isopropyl alcohol; under 760 Torr; Ambient temperature;

DOI:10.1016/S0040-4020(01)88510-0

Reference yield: 99.0%

isopropyl (2R,3S)-2-benzyloxy-4-cyclohexyl-3-<(S)-(1-phenylethyl)amino>butyrate (129397-43-9) → (2R,3S)-3-Amino-2-benzyloxy-4-cyclohexyl-butyric acid isopropyl ester

Guidance literature:

With hydrogen; palladium on activated charcoal;

upstream raw materials:

3-benzyloxy-4-cyclohexylmethyl-1-<(S)-1-phenylethyl>-2-azetidinone

isopropyl alcohol

Downstream raw materials:

2(R)-hydroxy-3(S)-amino-4-cyclohexylbutanoic acid 2-propyl ester

(2R,3S)-nor-C-statine hydrochloride

isopropyl (2R,3S)-3-acetamido-2-acetoxy-4-cyclohexylbutyrate