C₂₇H₂₈F₆N₂O₂

Base Information Edit

Chemical Name:C₂₇H₂₈F₆N₂O₂
CAS No.:1178515-20-2
Molecular Formula:C₂₇H₂₈F₆N₂O₂
Molecular Weight:526.522
Hs Code.:
Mol file:1178515-20-2.mol

C<sub>27</sub>H<sub>28</sub>F<sub>6</sub>N<sub>2</sub>O<sub>2</sub>

Synonyms:C₂₇H₂₈F₆N₂O₂

Suppliers and Price of C₂₇H₂₈F₆N₂O₂

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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Crysdot
(R)-5-((((S)-1-((R)-1-(3,5-Bis(trifluoromethyl)phenyl)ethoxy)-2-phenylbut-3-en-2-yl)amino)methyl)-5-vinylpyrrolidin-2-one 95+%
100mg
$ 437.00

Total 4 raw suppliers

Chemical Property of C₂₇H₂₈F₆N₂O₂ Edit

Chemical Property:

Purity/Quality:

99% ^*data from raw suppliers

(R)-5-((((S)-1-((R)-1-(3,5-Bis(trifluoromethyl)phenyl)ethoxy)-2-phenylbut-3-en-2-yl)amino)methyl)-5-vinylpyrrolidin-2-one 95+% ^*data from reagent suppliers

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Technology Process of C₂₇H₂₈F₆N₂O₂

There total 11 articles about C₂₇H₂₈F₆N₂O₂ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1214741-23-7
C₂₇H₂₆F₆N₂O₂

: 1178515-20-2
C₂₇H₂₈F₆N₂O₂

Guidance literature:: With sodium tris(acetoxy)borohydride; acetic acid; In toluene; at 25 ℃; for 6h;

Reference yield:

: 98-79-3
L-Pyroglutamic acid

: 1178515-20-2
C₂₇H₂₈F₆N₂O₂

Guidance literature:: Multi-step reaction with 7 steps

1.1: methanesulfonic acid / diethylene glycol dimethyl ether; toluene / 14.5 h / Inert atmosphere; Reflux; Dean-Stark

2.1: copper(l) chloride; 1,3-dimethyl-2-imidazolidinone; lithium hexamethyldisilazane; chloro-trimethyl-silane / tetrahydrofuran / 0.5 h / -60 - 10 °C / Inert atmosphere

2.2: 3.67 h / 5 - 25 °C

3.1: sodium hexamethyldisilazane / toluene / 1 h / 10 °C

3.2: 10 °C

4.1: lithium tri(t-butoxy)aluminum hydride / tetrahydrofuran / 14 h / -20 - 0 °C / Inert atmosphere

4.2: 2 h / 0 - 20 °C / Inert atmosphere

5.1: triethylamine / water; ethanol / 4 h / 25 °C

6.1: ethanol; toluene / Reflux

7.1: sodium tris(acetoxy)borohydride; acetic acid / toluene / 6 h / 25 °C

With 1,3-dimethyl-2-imidazolidinone; chloro-trimethyl-silane; methanesulfonic acid; lithium tri(t-butoxy)aluminum hydride; sodium hexamethyldisilazane; sodium tris(acetoxy)borohydride; acetic acid; triethylamine; copper(l) chloride; lithium hexamethyldisilazane; In tetrahydrofuran; ethanol; diethylene glycol dimethyl ether; water; toluene;

Reference yield:

: C₂₀H₂₁F₆NO

: 1178515-20-2
C₂₇H₂₈F₆N₂O₂

Guidance literature:: Multi-step reaction with 4 steps

1: methanol; toluene / 1 h

2: sodium hydroxide / toluene / 0.5 h / 25 °C

3: ethanol; toluene / Reflux

4: sodium tris(acetoxy)borohydride; acetic acid / toluene / 6 h / 25 °C

With sodium tris(acetoxy)borohydride; acetic acid; sodium hydroxide; In methanol; ethanol; toluene;