{(R)-1-(3,4-diethyl-benzyl)-2-[4-(1-methyl-piperidin-4-yl)-piperazin-1-yl]-2-oxo-ethyl}-carbamic acid tert-butylester

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Chemical Name:{(R)-1-(3,4-diethyl-benzyl)-2-[4-(1-methyl-piperidin-4-yl)-piperazin-1-yl]-2-oxo-ethyl}-carbamic acid tert-butylester
CAS No.:686297-86-9
Molecular Formula:C₂₈H₄₆N₄O₃
Molecular Weight:486.698
Hs Code.:

Synonyms:{(R)-1-(3,4-diethyl-benzyl)-2-[4-(1-methyl-piperidin-4-yl)-piperazin-1-yl]-2-oxo-ethyl}-carbamic acid tert-butylester

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Chemical Property of {(R)-1-(3,4-diethyl-benzyl)-2-[4-(1-methyl-piperidin-4-yl)-piperazin-1-yl]-2-oxo-ethyl}-carbamic acid tert-butylester

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Technology Process of {(R)-1-(3,4-diethyl-benzyl)-2-[4-(1-methyl-piperidin-4-yl)-piperazin-1-yl]-2-oxo-ethyl}-carbamic acid tert-butylester

There total 1 articles about {(R)-1-(3,4-diethyl-benzyl)-2-[4-(1-methyl-piperidin-4-yl)-piperazin-1-yl]-2-oxo-ethyl}-carbamic acid tert-butylester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 67.0%

: 686297-85-8
(R)-2-tert-butoxycarbonylamino-3-(3,4-diethyl-phenyl)-propionic acid

: 23995-88-2
1-(1-methyl-piperidin-4-yl)-piperazine

: 686297-86-9
{(R)-1-(3,4-diethyl-benzyl)-2-[4-(1-methyl-piperidin-4-yl)-piperazin-1-yl]-2-oxo-ethyl}-carbamic acid tert-butylester

Guidance literature:: (R)-2-tert-butoxycarbonylamino-3-(3,4-diethyl-phenyl)-propionic acid; With benzotriazol-1-ol; O-(benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate; N-ethyl-N,N-diisopropylamine; In tetrahydrofuran; DMF (N,N-dimethyl-formamide); at 20 ℃; for 0.5h;

1-(1-methyl-piperidin-4-yl)-piperazine; In tetrahydrofuran; DMF (N,N-dimethyl-formamide); for 4h;

Reference yield: 91.0%

: 686297-86-9
{(R)-1-(3,4-diethyl-benzyl)-2-[4-(1-methyl-piperidin-4-yl)-piperazin-1-yl]-2-oxo-ethyl}-carbamic acid tert-butylester

: 686297-87-0
(R)-2-amino-3-(3,4-diethyl-phenyl)-1-[4-(1-methyl-piperidin-4-yl)-piperazin-1-yl]-propan-1-one

Guidance literature:: {(R)-1-(3,4-diethyl-benzyl)-2-[4-(1-methyl-piperidin-4-yl)-piperazin-1-yl]-2-oxo-ethyl}-carbamic acid tert-butylester; With trifluoroacetic acid; In dichloromethane; at 20 ℃; for 1.5h;

With potassium carbonate; In dichloromethane; water;