(Z)-3-((4-((4-oxo-2-thioxothiazolidin-5-ylidene)methyl)benzyl)amino)benzoic acid

Base Information

Chemical Name:(Z)-3-((4-((4-oxo-2-thioxothiazolidin-5-ylidene)methyl)benzyl)amino)benzoic acid
CAS No.:1384338-81-1
Molecular Formula:C₁₈H₁₄N₂O₃S₂
Molecular Weight:370.453
Hs Code.:

Synonyms:(Z)-3-((4-((4-oxo-2-thioxothiazolidin-5-ylidene)methyl)benzyl)amino)benzoic acid

Suppliers and Price of (Z)-3-((4-((4-oxo-2-thioxothiazolidin-5-ylidene)methyl)benzyl)amino)benzoic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (Z)-3-((4-((4-oxo-2-thioxothiazolidin-5-ylidene)methyl)benzyl)amino)benzoic acid

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (Z)-3-((4-((4-oxo-2-thioxothiazolidin-5-ylidene)methyl)benzyl)amino)benzoic acid

There total 4 articles about (Z)-3-((4-((4-oxo-2-thioxothiazolidin-5-ylidene)methyl)benzyl)amino)benzoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 57.0%

: 141-84-4
2-thioxo-4-thiazolidinone

: 1384338-79-7
3-((4-formylbenzyl)amino)benzoic acid

: 1384338-81-1
(Z)-3-((4-((4-oxo-2-thioxothiazolidin-5-ylidene)methyl)benzyl)amino)benzoic acid

Guidance literature:: With piperidine; acetic acid; In ethanol; for 40h; Reflux;
DOI:10.1021/ml300047h

Reference yield:

: 40681-88-7
4-(1,3-dioxolan-2-yl)benzaldehyde

: 1384338-81-1
(Z)-3-((4-((4-oxo-2-thioxothiazolidin-5-ylidene)methyl)benzyl)amino)benzoic acid

Guidance literature:: Multi-step reaction with 3 steps

1: sodium cyanotrihydroborate / methanol / 20 °C

2: pyridinium p-toluenesulfonate / tetrahydrofuran; water / 20 °C

3: piperidine; acetic acid / ethanol / 40 h / Reflux

With piperidine; sodium cyanotrihydroborate; pyridinium p-toluenesulfonate; acetic acid; In tetrahydrofuran; methanol; ethanol; water; 3: |Knoevenagel Condensation;
DOI:10.1021/ml300047h

Reference yield:

: 623-27-8
terephthalaldehyde,

: 1384338-81-1
(Z)-3-((4-((4-oxo-2-thioxothiazolidin-5-ylidene)methyl)benzyl)amino)benzoic acid

Guidance literature:: Multi-step reaction with 4 steps

1: toluene-4-sulfonic acid / benzene / Reflux; Dean-Stark

2: sodium cyanotrihydroborate / methanol / 20 °C

3: pyridinium p-toluenesulfonate / tetrahydrofuran; water / 20 °C

4: piperidine; acetic acid / ethanol / 40 h / Reflux

With piperidine; sodium cyanotrihydroborate; pyridinium p-toluenesulfonate; toluene-4-sulfonic acid; acetic acid; In tetrahydrofuran; methanol; ethanol; water; benzene; 4: |Knoevenagel Condensation;
DOI:10.1021/ml300047h