dichloroplatinum(2+) 2-methylpiperidin-1-ide 6-methyl-2H-pyridin-1-ide (1:1:1)

Base Information

• Chemical Name: dichloroplatinum(2+) 2-methylpiperidin-1-ide 6-methyl-2H-pyridin-1-ide (1:1:1)
• CAS No.: 72151-34-9
• Molecular Formula: C12H20Cl2N2Pt
• Molecular Weight: 458.2906
• Mol file: 72151-34-9.mol

Synonyms:

Chemical Property of dichloroplatinum(2+) 2-methylpiperidin-1-ide 6-methyl-2H-pyridin-1-ide (1:1:1)

Chemical Property:

• Vapor Pressure: 16.4mmHg at 25°C
• Boiling Point: 118.8°C at 760 mmHg
• Flash Point: 8.3°C

Purity/Quality:

99%min ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of dichloroplatinum(2+) 2-methylpiperidin-1-ide 6-methyl-2H-pyridin-1-ide (1:1:1)

There total 8 articles about dichloroplatinum(2+) 2-methylpiperidin-1-ide 6-methyl-2H-pyridin-1-ide (1:1:1) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 44.0%

α-picoline (109-06-8) + trans-dichloro-bis(methyl cyanide)-platinum(II) (13869-42-6,13869-38-0,21264-32-4) → trans-Pt(2-methylpyridine)2Cl2 (72151-34-9,52646-75-0,52613-97-5)

Guidance literature:

In benzene; (N2); stirring (room temp., 15 h), pptn.; filtration, washing (benzene), drying (vac.); elem. anal.;

Reference yield:

α-picoline (109-06-8) + potassium tetrachloroplatinate(II) (10025-99-7) → trans-Pt(2-methylpyridine)2Cl2 (72151-34-9,52646-75-0,52613-97-5)

Guidance literature:

With NaCl or KCl; In water; refluxing of K2PtCl4 with excess 2-picoline until dissoln., addn. to excess concd. aq. NaCl or KCl, heating to 90°C (2 h, sepn. of oil); elem. anal.;

DOI:10.1016/S0020-1693(00)91945-5

Reference yield:

potassium trichloro(2-picoline)platinate (66705-99-5) → Pt(2-picoline)2Cl2 (72151-34-9,52646-75-0,52613-97-5) + trans-Pt(2-picoline)(pyrimidine)Cl2 (1148053-03-5,1149390-77-1) + trans,trans-Cl2(2-picoline)Pt(μ-pyrimidine)Pt(2-picoline)Cl2 (1148053-14-8)

Guidance literature:

Multi-step reaction with 2 steps

1: NaCl / water

2: chloroform

With NaCl; In chloroform; water;

DOI:10.1016/j.ica.2008.07.003

upstream raw materials:

α-picoline

trans-dichloro-bis(methyl cyanide)-platinum(II)

potassium tetrachloroplatinate(II)

cis-{Pt(2-methylpyridine)2Cl₂}

Downstream raw materials:

trans-Pt(2-methylpyridine)2Cl2

AMD443

Refernces

• 1、 Mostafa Hossain,Ogura. "Platinum(II) complexes of substituted pyridine and pyrazole derivatives". . p. 373 - 378. Retrieved 2007/10/03.
• 2、 Bondarenko, V. S.,Korniets, E. D.,Sokolenko, B. A.,Kovrova, N. B.. "Hindered rotation of ligands in cis- complexes". . p. 388 - 389. Retrieved 2007/10/02.