CID 6918325

Base Information

Chemical Name:CID 6918325
CAS No.:181630-15-9
Molecular Formula:C₆H₁₀Cl₂N₂Pt
Molecular Weight:376.145
Hs Code.:
Wikidata:Q7191060
Mol file:181630-15-9.mol

Synonyms:AMD 473;AMD-473;AMD473;amminedichloro(2-methylpyridine)platinum(II);Cis-amminedichloro(2-methylpyridine)platinum(II);JM-473;JM473;picoplatin;ZD 0473;ZD-0473;ZD0473

Suppliers and Price of CID 6918325

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
Picoplatin
5mg
$ 948.00

TRC
Picoplatin
10mg
$ 870.00

TRC
Picoplatin
5mg
$ 545.00

Medical Isotopes, Inc.
Picoplatin 99%
50 mg
$ 1500.00

Biosynth Carbosynth
Picoplatin
10 mg
$ 85.00

Biosynth Carbosynth
Picoplatin
50 mg
$ 297.50

American Custom Chemicals Corporation
PICOPLATIN 95.00%
5MG
$ 505.81

AK Scientific
Picoplatin
10mg
$ 164.00

Total 36 raw suppliers

Chemical Property of CID 6918325

Chemical Property:

Vapor Pressure:13.5mmHg at 25°C
Boiling Point:127.5°Cat760mmHg
Flash Point:26.1°C
PSA：12.89000
Density:g/cm³
LogP:2.76650
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:0
Exact Mass:374.986898
Heavy Atom Count:11
Complexity:54.9

Purity/Quality:

98%,99%, ^*data from raw suppliers

Picoplatin ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC=CC=N1.N.Cl[Pt]Cl
Uses Treatment of cancer. Picoplatin is an extended spectrum of antineoplastic activity.

Technology Process of CID 6918325

There total 11 articles about CID 6918325 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 109-06-8
α-picoline

: 20574-25-8
K{PtaCl₃}*H₂O

: 181630-15-9,865321-51-3
cis-amminedichlorido(2-methylpyridine)platinum(II)

Guidance literature:: α-picoline; K{PtaCl₃}*H₂O; With potassium chloride; potassium iodide; In water; for 3h;

With water; silver nitrate; for 6h; Darkness;

With hydrogenchloride; In water; for 72h;

Reference yield: 89.0%

: 7647-01-0,15364-23-5
hydrogenchloride

: 1200317-36-7
ammineiodochloro(2-picoline)platinum(II)

: 181630-15-9,865321-51-3
cis-amminedichlorido(2-methylpyridine)platinum(II)

Guidance literature:: ammineiodochloro(2-picoline)platinum(II); With silver nitrate; In water; acetone; for 5h; Darkness;

hydrogenchloride; In water; at 20 ℃;

Reference yield: 68.5%

: 109-06-8
α-picoline

: 15663-27-1
cisplatin

: 181630-15-9,865321-51-3
AMD443

Guidance literature:: In water; Pt-complex suspended in H2O, 2-picoline added, stirred at 348 K for 2.5 h, refluxed for 30 min, solvent removed, HCl added, stirred for 5 h at 378 K, cooled to 277 K for 24 h; filtered, heated to 378 K for 6 h, cooled to 277 K, filtered, washed with H2O, EtOH, Et2O, dried under vac.;
DOI:10.1016/j.ica.2008.02.039