(S)-3-(4-(2-fluoroethoxy)phenyl)-2-(2-(4-((2-sulfamoylbenzo[d]thiazol-6-yloxy)methyl)-1H-1,2,3-triazol-1-yl)acetamido)propanoic acid

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Chemical Name:(S)-3-(4-(2-fluoroethoxy)phenyl)-2-(2-(4-((2-sulfamoylbenzo[d]thiazol-6-yloxy)methyl)-1H-1,2,3-triazol-1-yl)acetamido)propanoic acid
CAS No.:1071471-15-2
Molecular Formula:C₂₃H₂₃FN₆O₇S₂
Molecular Weight:578.602
Hs Code.:

Synonyms:(S)-3-(4-(2-fluoroethoxy)phenyl)-2-(2-(4-((2-sulfamoylbenzo[d]thiazol-6-yloxy)methyl)-1H-1,2,3-triazol-1-yl)acetamido)propanoic acid

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Chemical Property of (S)-3-(4-(2-fluoroethoxy)phenyl)-2-(2-(4-((2-sulfamoylbenzo[d]thiazol-6-yloxy)methyl)-1H-1,2,3-triazol-1-yl)acetamido)propanoic acid

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Technology Process of (S)-3-(4-(2-fluoroethoxy)phenyl)-2-(2-(4-((2-sulfamoylbenzo[d]thiazol-6-yloxy)methyl)-1H-1,2,3-triazol-1-yl)acetamido)propanoic acid

There total 7 articles about (S)-3-(4-(2-fluoroethoxy)phenyl)-2-(2-(4-((2-sulfamoylbenzo[d]thiazol-6-yloxy)methyl)-1H-1,2,3-triazol-1-yl)acetamido)propanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: C₂₄H₂₅FN₆O₇S₂

: 1071471-15-2
(S)-3-(4-(2-fluoroethoxy)phenyl)-2-(2-(4-((2-sulfamoylbenzo[d]thiazol-6-yloxy)methyl)-1H-1,2,3-triazol-1-yl)acetamido)propanoic acid

Guidance literature:: With lithium hydroxide; water; In tetrahydrofuran; tert-butyl alcohol; at 20 ℃; for 2h;

Reference yield:

: 452-35-7
6-ethoxybenzothiazole-2-sulfonamide

: 1071471-15-2
(S)-3-(4-(2-fluoroethoxy)phenyl)-2-(2-(4-((2-sulfamoylbenzo[d]thiazol-6-yloxy)methyl)-1H-1,2,3-triazol-1-yl)acetamido)propanoic acid

Guidance literature:: Multi-step reaction with 4 steps

1.1: aluminum (III) chloride / dichloromethane / 24 h / 0 - 20 °C

2.1: sodium hydroxide / methanol; N,N-dimethyl-formamide / 0.75 h / 23 °C

2.2: 2.5 h

3.1: copper(II) sulfate; sodium L-ascorbate / tetrahydrofuran; water; tert-butyl alcohol / 12 h

4.1: lithium hydroxide; water / tetrahydrofuran; tert-butyl alcohol / 2 h / 20 °C

With aluminum (III) chloride; lithium hydroxide; sodium hydroxide; water; copper(II) sulfate; sodium L-ascorbate; In tetrahydrofuran; methanol; dichloromethane; water; N,N-dimethyl-formamide; tert-butyl alcohol;

Reference yield:

: 29927-14-8
6-hydroxy-2-benzothiazolesulfonamide

: 1071471-15-2
(S)-3-(4-(2-fluoroethoxy)phenyl)-2-(2-(4-((2-sulfamoylbenzo[d]thiazol-6-yloxy)methyl)-1H-1,2,3-triazol-1-yl)acetamido)propanoic acid

Guidance literature:: Multi-step reaction with 3 steps

1.1: sodium hydroxide / methanol; N,N-dimethyl-formamide / 0.75 h / 23 °C

1.2: 2.5 h

2.1: copper(II) sulfate; sodium L-ascorbate / tetrahydrofuran; water; tert-butyl alcohol / 12 h

3.1: lithium hydroxide; water / tetrahydrofuran; tert-butyl alcohol / 2 h / 20 °C

With lithium hydroxide; sodium hydroxide; water; copper(II) sulfate; sodium L-ascorbate; In tetrahydrofuran; methanol; water; N,N-dimethyl-formamide; tert-butyl alcohol;