Diformyldapsone

Base Information

Chemical Name:Diformyldapsone
CAS No.:6784-25-4
Molecular Formula:C14H12 N2 O4 S
Molecular Weight:304.326
Hs Code.:2924299090
NSC Number:53674
UNII:TF8F6OBI8Q
DSSTox Substance ID:DTXSID70218079
Nikkaji Number:J15.121A
Wikidata:Q83094830
ChEMBL ID:CHEMBL2001327
Mol file:6784-25-4.mol

Synonyms:4,4'-diformamidodiphenylsulfone;4,4'-sulfonylbisformanilide;DFD;DFDDS;diformamido diphenylsulfone;diformyl dapsone;WR-6798

Suppliers and Price of Diformyldapsone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
Diformyldapsone
25mg
$ 165.00

Total 12 raw suppliers

Chemical Property of Diformyldapsone

Chemical Property:

Refractive Index:1.6930 (estimate)
Boiling Point:643.4oC at 760 mmHg
Flash Point:342.9oC
PSA：100.72000
Density:1.3704 (rough estimate)
LogP:4.15460
XLogP3:0.7
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:4
Exact Mass:304.05177804
Heavy Atom Count:21
Complexity:408

Purity/Quality:

99% ^*data from raw suppliers

Diformyldapsone ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=CC=C1NC=O)S(=O)(=O)C2=CC=C(C=C2)NC=O
Uses Diformyldapsone is an effective treatment of murine and human P. carinii pneumonitis. Also, it is a derivative of the parent compound, Dapsone (D193250), which is an antibacterial used in the treatment of dermatitis herpetiformis.

Technology Process of Diformyldapsone

There total 3 articles about Diformyldapsone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

: 64-18-6
formic acid

: 80-08-0
dapsone

: 6784-25-4
N,N'-(4,4'-sulfonylbis(4,1-phenylene))diformamide

Guidance literature:: With Na⁺-MMT-[pmim]HSO₄; In neat (no solvent); at 60 ℃; for 0.416667h; chemoselective reaction;
DOI:10.1007/s11164-015-2116-0

Reference yield:

: 80-07-9,30605-10-8,85228-26-8,36313-66-3
4,4'-dichlorodiphenyl sulphone

: 6784-25-4
N,N'-(4,4'-sulfonylbis(4,1-phenylene))diformamide

Guidance literature:: Multi-step reaction with 2 steps

1: water; copper; copper (I)-bromide; ammonia / 200 °C

With ammonia; water; copper; copper(I) bromide;
DOI:10.1021/ja01227a035