N1-(4-Cyanobutyl)-N1-(phenylmethoxy)-N4-[5-[(phenylmethoxy)amino]pentyl]butanediamide

Base Information

Chemical Name:N1-(4-Cyanobutyl)-N1-(phenylmethoxy)-N4-[5-[(phenylmethoxy)amino]pentyl]butanediamide
CAS No.:129245-23-4
Molecular Formula:C₂₈H₃₈N₄O₄
Molecular Weight:494.634
Hs Code.:
DSSTox Substance ID:DTXSID801127053

Synonyms:SCHEMBL9437259;LSUTVDADTTVHAX-UHFFFAOYSA-N;DTXSID801127053;6,17-Bis(benzyloxy)-7,10-dioxo-6,11,17-triazaheptadecane-nitrile;N1-(4-Cyanobutyl)-N1-(phenylmethoxy)-N4-[5-[(phenylmethoxy)amino]pentyl]butanediamide;129245-23-4

Suppliers and Price of N1-(4-Cyanobutyl)-N1-(phenylmethoxy)-N4-[5-[(phenylmethoxy)amino]pentyl]butanediamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of N1-(4-Cyanobutyl)-N1-(phenylmethoxy)-N4-[5-[(phenylmethoxy)amino]pentyl]butanediamide

Chemical Property:

XLogP3:3
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:19
Exact Mass:494.28930571
Heavy Atom Count:36
Complexity:639

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC=C(C=C1)CONCCCCCNC(=O)CCC(=O)N(CCCCC#N)OCC2=CC=CC=C2

Technology Process of N1-(4-Cyanobutyl)-N1-(phenylmethoxy)-N4-[5-[(phenylmethoxy)amino]pentyl]butanediamide

There total 8 articles about N1-(4-Cyanobutyl)-N1-(phenylmethoxy)-N4-[5-[(phenylmethoxy)amino]pentyl]butanediamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

: 129245-22-3
N-(4-cyanobutyl)-3-<<5-<(benzyloxy)-tert-butoxy-carbonylamino>pentyl>carbamoyl>-O-benzylpropionohydroxamic acid

: 129245-23-4
N-(4-cyanobutyl)-3-<<5-<(benzyloxy)amino>pentyl>carbamoyl>-O-benzylpropionohydroxamic acid

Guidance literature:: With trifluoroacetic acid; In dichloromethane; at 0 - 20 ℃; for 0.75h;
DOI:10.1021/jm00115a006

Reference yield:

: 144-55-8
sodium hydrogencarbonate

: 129245-22-3
N-(4-cyanobutyl)-3-<<5-<(benzyloxy)-tert-butoxy-carbonylamino>pentyl>carbamoyl>-O-benzylpropionohydroxamic acid

: 129245-23-4
N-(4-cyanobutyl)-3-<<5-<(benzyloxy)amino>pentyl>carbamoyl>-O-benzylpropionohydroxamic acid

Guidance literature:: With trifluoroacetic acid; In dichloromethane;

Reference yield:

: 112139-60-3
N-(4-Cyanobutyl)-N-(benzyloxy)succinamic Acid

: 129245-23-4
N-(4-cyanobutyl)-3-<<5-<(benzyloxy)amino>pentyl>carbamoyl>-O-benzylpropionohydroxamic acid

Guidance literature:: Multi-step reaction with 2 steps

1: 65 percent / 4-dimethylaminopyridine, 1,3-dicyclohexylcarbodiimide / CH₂Cl₂ / 1.) 0 deg C, 45 min, 2.) room temp., 19 h

2: 83 percent / TFA / 0.33 h / Ambient temperature

With dmap; dicyclohexyl-carbodiimide; trifluoroacetic acid; In dichloromethane;
DOI:10.1016/S0040-4020(01)81074-7