4-(methoxy)-2,6-diisopropylaniline

Base Information

• Chemical Name: 4-(methoxy)-2,6-diisopropylaniline
• CAS No.: 1394159-51-3
• Molecular Formula: C₁₃H₂₁NO
• Molecular Weight: 207.316
• Mol file: 1394159-51-3.mol

Synonyms:4-(methoxy)-2,6-diisopropylaniline

Chemical Property of 4-(methoxy)-2,6-diisopropylaniline

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4-(methoxy)-2,6-diisopropylaniline

There total 4 articles about 4-(methoxy)-2,6-diisopropylaniline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

methanol (67-56-1) + 4-iodo-2,6-diisopropylaniline (140411-20-7) → 4-(methoxy)-2,6-diisopropylaniline (1394159-51-3)

Guidance literature:

4-iodo-2,6-diisopropylaniline; With copper(l) iodide; 3,4,7,8-Tetramethyl-o-phenanthrolin; caesium carbonate; In toluene; at 80 ℃; for 0.333333h; Inert atmosphere;

methanol; In toluene; at 80 ℃; for 24h; Inert atmosphere;

DOI:10.1021/jo3012418

Reference yield: 73.0%

methanol (67-56-1) + N,N'-bis(4-iodo-2,6-diisopropylphenyl)1,4-diazabutadiene (934008-46-5) → 4-(methoxy)-2,6-diisopropylaniline (1394159-51-3)

Guidance literature:

With copper(l) iodide; 1,10-Phenanthroline; caesium carbonate; for 10h; Sealed tube; Heating;

DOI:10.1055/s-0033-1340105

Reference yield:

2,6-diisopropylbenzenamine (24544-04-5) → 4-(methoxy)-2,6-diisopropylaniline (1394159-51-3)

Guidance literature:

Multi-step reaction with 3 steps

1: sodium carbonate; iodine / cyclohexane; water / 11 h / 20 °C

2: formic acid / water; methanol

3: copper(l) iodide; 1,10-Phenanthroline; caesium carbonate / 10 h / Sealed tube; Heating

With copper(l) iodide; formic acid; 1,10-Phenanthroline; iodine; sodium carbonate; caesium carbonate; In methanol; cyclohexane; water;

DOI:10.1055/s-0033-1340105

upstream raw materials:

methanol

4-iodo-2,6-diisopropylaniline

N,N'-bis(4-iodo-2,6-diisopropylphenyl)1,4-diazabutadiene

2,6-diisopropylbenzenamine

Downstream raw materials:

(E,E)-N,N?'-(pyridine-2,6-diylbis-(methanylylidene))bis(4-methoxy-2,6-diisopropylaniline)

[1,3-bis(4-methoxy-2,6-diisopropyl)phenyl]imidazolium chloride

1,3-bis-(4-methoxy-2,6-diisopropylphenyl)-4,5-dihydroimidazolinium chloride

N,N'-bis(4-methoxy-2,6-diisopropylphenylamino)ethane-1,2-diamine