2,4-dimethoxy-6-(3,5-dimethylbenzyl)-5-ethylpyrimidine

Base Information

Chemical Name:2,4-dimethoxy-6-(3,5-dimethylbenzyl)-5-ethylpyrimidine
CAS No.:225232-56-4
Molecular Formula:C₁₇H₂₂N₂O₂
Molecular Weight:286.374
Hs Code.:

Synonyms:2,4-dimethoxy-6-(3,5-dimethylbenzyl)-5-ethylpyrimidine

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 2,4-dimethoxy-6-(3,5-dimethylbenzyl)-5-ethylpyrimidine

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Technology Process of 2,4-dimethoxy-6-(3,5-dimethylbenzyl)-5-ethylpyrimidine

There total 3 articles about 2,4-dimethoxy-6-(3,5-dimethylbenzyl)-5-ethylpyrimidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

: 67-56-1
methanol

: 225232-08-6
2,4-dichloro-6-(3,5-dimethylbenzyl)-5-ethylpyrimidine

: 225232-56-4
2,4-dimethoxy-6-(3,5-dimethylbenzyl)-5-ethylpyrimidine

Guidance literature:: With sodium methylate; for 4h; Heating;
DOI:10.1080/00397919908086130

Reference yield:

: 1780-38-7
2,4,6-trichloro-5-ethylpyrimidine

: 225232-56-4
2,4-dimethoxy-6-(3,5-dimethylbenzyl)-5-ethylpyrimidine

Guidance literature:: Multi-step reaction with 2 steps

1: 88 percent / tetrahydrofuran / -78 °C

2: 93 percent / NaOMe / 4 h / Heating

With sodium methylate; In tetrahydrofuran;
DOI:10.1080/00397919908086130

Reference yield:

: 29875-08-9
3,5-dimethylbenzyl magnesium chloride

: 225232-56-4
2,4-dimethoxy-6-(3,5-dimethylbenzyl)-5-ethylpyrimidine

Guidance literature:: Multi-step reaction with 2 steps

1: 88 percent / tetrahydrofuran / -78 °C

2: 93 percent / NaOMe / 4 h / Heating

With sodium methylate; In tetrahydrofuran;
DOI:10.1080/00397919908086130