3-(tert-butyldimethylsiloxy)-6-phenylhexanoic acid N,N-methoxymethylamide

Base Information

Chemical Name:3-(tert-butyldimethylsiloxy)-6-phenylhexanoic acid N,N-methoxymethylamide
CAS No.:1316253-74-3
Molecular Formula:C₂₀H₃₅NO₃Si
Molecular Weight:365.588
Hs Code.:

Synonyms:3-(tert-butyldimethylsiloxy)-6-phenylhexanoic acid N,N-methoxymethylamide

Suppliers and Price of 3-(tert-butyldimethylsiloxy)-6-phenylhexanoic acid N,N-methoxymethylamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 3-(tert-butyldimethylsiloxy)-6-phenylhexanoic acid N,N-methoxymethylamide

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 3-(tert-butyldimethylsiloxy)-6-phenylhexanoic acid N,N-methoxymethylamide

There total 4 articles about 3-(tert-butyldimethylsiloxy)-6-phenylhexanoic acid N,N-methoxymethylamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

: 1316253-55-0
3-hydroxy-6-phenylhexanoic acid N,N-methoxymethylamide

: 18162-48-6
tert-butyldimethylsilyl chloride

: 1316253-74-3
3-(tert-butyldimethylsiloxy)-6-phenylhexanoic acid N,N-methoxymethylamide

Guidance literature:: With 1H-imidazole; dmap; In N,N-dimethyl-formamide; at 0 - 20 ℃; Inert atmosphere;
DOI:10.1039/c1cc11746g

Reference yield:

: 1316253-39-0
(E)-6-phenyl-3-hexenoic acid N,O-dimethylhydroxylamide

: 1316253-74-3
3-(tert-butyldimethylsiloxy)-6-phenylhexanoic acid N,N-methoxymethylamide

Guidance literature:: Multi-step reaction with 3 steps

1: (R)-(+)-1,1'-bi-2-naphthol; bis(norbornadiene)rhodium(l)tetrafluoroborate / tetrahydrofuran / 0 - 40 °C / Inert atmosphere

2: sodium perborate tetrahydrate / tetrahydrofuran; water / 0 - 20 °C / Inert atmosphere

3: 1H-imidazole; dmap / N,N-dimethyl-formamide / 0 - 20 °C / Inert atmosphere

With 1H-imidazole; dmap; bis(norbornadiene)rhodium(l)tetrafluoroborate; (R)-(+)-1,1'-bi-2-naphthol; In tetrahydrofuran; water; N,N-dimethyl-formamide;
DOI:10.1039/c1cc11746g

Reference yield:

: 1316253-52-7
3-(4,4,6-trimethyl-1,3,2-dioxaborato)-6-phenylhexanoic acid N,N-methoxymethylamide

: 1316253-74-3
3-(tert-butyldimethylsiloxy)-6-phenylhexanoic acid N,N-methoxymethylamide

Guidance literature:: Multi-step reaction with 2 steps

1: sodium perborate tetrahydrate / tetrahydrofuran; water / 0 - 20 °C / Inert atmosphere

2: 1H-imidazole; dmap / N,N-dimethyl-formamide / 0 - 20 °C / Inert atmosphere

With 1H-imidazole; dmap; In tetrahydrofuran; water; N,N-dimethyl-formamide;
DOI:10.1039/c1cc11746g