(E)-6-phenyl-3-hexenoic acid N,O-dimethylhydroxylamide

Base Information

• Chemical Name: (E)-6-phenyl-3-hexenoic acid N,O-dimethylhydroxylamide
• CAS No.: 1316253-39-0
• Molecular Formula: C₁₄H₁₉NO₂
• Molecular Weight: 233.31
• Mol file: 1316253-39-0.mol

Synonyms:(E)-6-phenyl-3-hexenoic acid N,O-dimethylhydroxylamide

Chemical Property of (E)-6-phenyl-3-hexenoic acid N,O-dimethylhydroxylamide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (E)-6-phenyl-3-hexenoic acid N,O-dimethylhydroxylamide

There total 1 articles about (E)-6-phenyl-3-hexenoic acid N,O-dimethylhydroxylamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

N,O-dimethylhydroxylamine*hydrochloride (6638-79-5) + (E)-6-phenyl-3-hexenoic acid (1016225-28-7) → (E)-6-phenyl-3-hexenoic acid N,O-dimethylhydroxylamide (1316253-39-0)

Guidance literature:

(E)-6-phenyl-3-hexenoic acid; With 1,1'-carbonyldiimidazole; In dichloromethane; at 0 ℃; for 0.5h; Inert atmosphere;

N,O-dimethylhydroxylamine*hydrochloride; In dichloromethane; at 0 - 20 ℃; for 5h; Inert atmosphere;

DOI:10.1039/c1cc11746g

Reference yield: 79.0%

4,4,6-trimethyl-1,3,2-dioxaborinane (10199-14-1,23894-82-8) + (E)-6-phenyl-3-hexenoic acid N,O-dimethylhydroxylamide (1316253-39-0) → 3-(4,4,6-trimethyl-1,3,2-dioxaborato)-6-phenylhexanoic acid N,N-methoxymethylamide (1316253-52-7)

Guidance literature:

With bis(norbornadiene)rhodium(l)tetrafluoroborate; (R)-(+)-1,1'-bi-2-naphthol; In tetrahydrofuran; at 0 - 40 ℃; Inert atmosphere;

DOI:10.1039/c1cc11746g

Reference yield:

C9H11BO2 (1316253-37-8) + (E)-6-phenyl-3-hexenoic acid N,O-dimethylhydroxylamide (1316253-39-0) → C23H30BNO4

Guidance literature:

With bis(norbornadiene)rhodium(l)tetrafluoroborate; (R)-(+)-1,1'-bi-2-naphthol; In tetrahydrofuran; at 0 - 20 ℃; Inert atmosphere;

DOI:10.1039/c1cc11746g

upstream raw materials:

N,O-dimethylhydroxylamine*hydrochloride

(E)-6-phenyl-3-hexenoic acid

Downstream raw materials:

3-hydroxy-6-phenylhexanoic acid N,N-methoxymethylamide

3-(tert-butyldimethylsiloxy)-6-phenylhexanoic acid N,N-methoxymethylamide

3-(tert-butyldimethylsiloxy)-6-phenylhexanoic acid phenyl ketone

3-(tert-butyldimethylsiloxy)-6-phenylhexanal