tert-butyl 4-hydroxy-4-(4-(trimethylsilyl)phenyl)-1-piperidinecarboxylate

Base Information

Chemical Name:tert-butyl 4-hydroxy-4-(4-(trimethylsilyl)phenyl)-1-piperidinecarboxylate
CAS No.:1356399-85-3
Molecular Formula:C₁₉H₃₁NO₃Si
Molecular Weight:349.546
Hs Code.:

Synonyms:tert-butyl 4-hydroxy-4-(4-(trimethylsilyl)phenyl)-1-piperidinecarboxylate

Suppliers and Price of tert-butyl 4-hydroxy-4-(4-(trimethylsilyl)phenyl)-1-piperidinecarboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of tert-butyl 4-hydroxy-4-(4-(trimethylsilyl)phenyl)-1-piperidinecarboxylate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of tert-butyl 4-hydroxy-4-(4-(trimethylsilyl)phenyl)-1-piperidinecarboxylate

There total 2 articles about tert-butyl 4-hydroxy-4-(4-(trimethylsilyl)phenyl)-1-piperidinecarboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.0%

: 109384-19-2
t-butyl 4-hydroxy piperidine-1-carboxylate

: 574755-28-5
(4-(5,5-dimethyl-1,3,2-dioxaborinan-2-yl)phenyl)trimethylsilane

: 1356399-85-3
tert-butyl 4-hydroxy-4-(4-(trimethylsilyl)phenyl)-1-piperidinecarboxylate

Guidance literature:: With bis(1,5-cyclooctadiene)nickel ⁽⁰⁾; potassium tert-butylate; chlorobenzene; cesium fluoride; 1,3-bis[2,6-diisopropylphenyl]imidazolium chloride; In toluene; at 80 ℃; for 5h; Inert atmosphere;
DOI:10.1039/c1cc10826c

Reference yield:

: 17865-11-1
(4-(trimethylsilyl)phenyl)boronic acid

: 1356399-85-3
tert-butyl 4-hydroxy-4-(4-(trimethylsilyl)phenyl)-1-piperidinecarboxylate

Guidance literature:: Multi-step reaction with 2 steps

1: toluene / Reflux; Inert atmosphere

2: bis(1,5-cyclooctadiene)nickel ⁽⁰⁾; potassium tert-butylate; chlorobenzene; cesium fluoride; 1,3-bis[2,6-diisopropylphenyl]imidazolium chloride / toluene / 5 h / 80 °C / Inert atmosphere

With bis(1,5-cyclooctadiene)nickel ⁽⁰⁾; potassium tert-butylate; chlorobenzene; cesium fluoride; 1,3-bis[2,6-diisopropylphenyl]imidazolium chloride; In toluene;
DOI:10.1039/c1cc10826c