ethyl 2-ethoxy-3-{4-[2-(2-benzyloxycarbazol-9-yl)ethoxy]phenyl}propionate

Base Information

• Chemical Name: ethyl 2-ethoxy-3-{4-[2-(2-benzyloxycarbazol-9-yl)ethoxy]phenyl}propionate
• CAS No.: 859831-77-9
• Molecular Formula: C₃₄H₃₅NO₅
• Molecular Weight: 537.656
• Mol file: 859831-77-9.mol

Synonyms:ethyl 2-ethoxy-3-{4-[2-(2-benzyloxycarbazol-9-yl)ethoxy]phenyl}propionate

Chemical Property of ethyl 2-ethoxy-3-{4-[2-(2-benzyloxycarbazol-9-yl)ethoxy]phenyl}propionate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of ethyl 2-ethoxy-3-{4-[2-(2-benzyloxycarbazol-9-yl)ethoxy]phenyl}propionate

There total 6 articles about ethyl 2-ethoxy-3-{4-[2-(2-benzyloxycarbazol-9-yl)ethoxy]phenyl}propionate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

ethyl 2-ethoxy-3-{4-[2-(2-benzyloxycarbazol-9-yl)ethoxy]phenyl}-2-propenoate (859831-71-3) → ethyl 2-ethoxy-3-{4-[2-(2-benzyloxycarbazol-9-yl)ethoxy]phenyl}propionate (859831-77-9)

Guidance literature:

With hydrogen; palladium on activated charcoal; In ethyl acetate; for 5h; under 3102.89 Torr;

DOI:10.1016/j.bmc.2005.04.018

Reference yield:

4-(2-(2-benzyloxycarbazol-9-yl)ethoxy)benzaldehyde (859831-66-6) → ethyl 2-ethoxy-3-{4-[2-(2-benzyloxycarbazol-9-yl)ethoxy]phenyl}propionate (859831-77-9)

Guidance literature:

Multi-step reaction with 2 steps

1: sodium hydride / tetrahydrofuran / 0 - 20 °C

2: hydrogen / Pd/C / ethyl acetate / 5 h / 3102.89 Torr

With hydrogen; sodium hydride; palladium on activated charcoal; In tetrahydrofuran; ethyl acetate; 1: Horner-Wadsworth-Emmons reaction;

DOI:10.1016/j.bmc.2005.04.018

Reference yield:

2-hydroxycarbazole (86-79-3) → ethyl 2-ethoxy-3-{4-[2-(2-benzyloxycarbazol-9-yl)ethoxy]phenyl}propionate (859831-77-9)

Guidance literature:

Multi-step reaction with 4 steps

1: tetrabutylammonium hydrogen sulfate; potassium carbonate / ethyl acetate / Heating

2: sodium hydride / tetrahydrofuran / 0 - 20 °C

3: sodium hydride / tetrahydrofuran / 0 - 20 °C

4: hydrogen / Pd/C / ethyl acetate / 5 h / 3102.89 Torr

With hydrogen; tetra(n-butyl)ammonium hydrogensulfate; sodium hydride; potassium carbonate; palladium on activated charcoal; In tetrahydrofuran; ethyl acetate; 3: Horner-Wadsworth-Emmons reaction;

DOI:10.1016/j.bmc.2005.04.018

upstream raw materials:

ethyl 2-ethoxy-3-{4-[2-(2-benzyloxycarbazol-9-yl)ethoxy]phenyl}-2-propenoate

4-(2-(2-benzyloxycarbazol-9-yl)ethoxy)benzaldehyde

2-hydroxycarbazole

ethyl 2-ethoxy-2-(diethylphosphono)acetate