ethyl 2,3-dideoxy-4-O-(3'R,4'S)-(3'-methylazetidin-2'-on-4'-yl)-6-O-trityl-α-D-erythro-hexopyranoside

Base Information

Chemical Name:ethyl 2,3-dideoxy-4-O-(3'R,4'S)-(3'-methylazetidin-2'-on-4'-yl)-6-O-trityl-α-D-erythro-hexopyranoside
CAS No.:495379-09-4
Molecular Formula:C₃₁H₃₅NO₅
Molecular Weight:501.623
Hs Code.:

Synonyms:ethyl 2,3-dideoxy-4-O-(3'R,4'S)-(3'-methylazetidin-2'-on-4'-yl)-6-O-trityl-α-D-erythro-hexopyranoside

Suppliers and Price of ethyl 2,3-dideoxy-4-O-(3'R,4'S)-(3'-methylazetidin-2'-on-4'-yl)-6-O-trityl-α-D-erythro-hexopyranoside

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of ethyl 2,3-dideoxy-4-O-(3'R,4'S)-(3'-methylazetidin-2'-on-4'-yl)-6-O-trityl-α-D-erythro-hexopyranoside

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of ethyl 2,3-dideoxy-4-O-(3'R,4'S)-(3'-methylazetidin-2'-on-4'-yl)-6-O-trityl-α-D-erythro-hexopyranoside

There total 3 articles about ethyl 2,3-dideoxy-4-O-(3'R,4'S)-(3'-methylazetidin-2'-on-4'-yl)-6-O-trityl-α-D-erythro-hexopyranoside which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 54.0%

: 1189-71-5
isocyanate de chlorosulfonyle

: 495378-95-5
ethyl 2,3-dideoxy-(Z)-4-O-propenyl-6-O-trityl-α-D-erythro-hexopyranoside

: 495379-09-4
ethyl 2,3-dideoxy-4-O-(3'R,4'S)-(3'-methylazetidin-2'-on-4'-yl)-6-O-trityl-α-D-erythro-hexopyranoside

Guidance literature:: isocyanate de chlorosulfonyle; ethyl 2,3-dideoxy-(Z)-4-O-propenyl-6-O-trityl-α-D-erythro-hexopyranoside; With sodium carbonate; In toluene; at -78 ℃; for 1.5h;

With [(CH₃OC₂H₄O)2AlH₂]Na; In toluene; at -78 ℃; for 0.5h;
DOI:10.1016/S0008-6215(02)00139-8

Reference yield:

: 495378-93-3
ethyl 2,3-dideoxy-6-O-trityl-α-D-erythro-hexopyranoside

: 495379-09-4
ethyl 2,3-dideoxy-4-O-(3'R,4'S)-(3'-methylazetidin-2'-on-4'-yl)-6-O-trityl-α-D-erythro-hexopyranoside

Guidance literature:: Multi-step reaction with 3 steps

1.1: 72 percent / KOH; Bu₄NBr / toluene / 2 h

2.1: 86 percent / t-BuOK / dimethylsulfoxide / 1.5 h / 50 °C

3.1: Na₂CO₃ / toluene / 1.5 h / -78 °C

3.2: 54 percent / [(CH₃OC₂H₄O)2AlH₂]Na / toluene / 0.5 h / -78 °C

With potassium hydroxide; potassium tert-butylate; tetrabutylammomium bromide; sodium carbonate; In dimethyl sulfoxide; toluene;
DOI:10.1016/S0008-6215(02)00139-8

Reference yield:

: 495378-94-4
ethyl 4-O-allyl-2,3-dideoxy-6-O-trityl-α-D-erythro-hexopyranoside

: 495379-09-4
ethyl 2,3-dideoxy-4-O-(3'R,4'S)-(3'-methylazetidin-2'-on-4'-yl)-6-O-trityl-α-D-erythro-hexopyranoside

Guidance literature:: Multi-step reaction with 2 steps

1.1: 86 percent / t-BuOK / dimethylsulfoxide / 1.5 h / 50 °C

2.1: Na₂CO₃ / toluene / 1.5 h / -78 °C

2.2: 54 percent / [(CH₃OC₂H₄O)2AlH₂]Na / toluene / 0.5 h / -78 °C

With potassium tert-butylate; sodium carbonate; In dimethyl sulfoxide; toluene;
DOI:10.1016/S0008-6215(02)00139-8