(R)-N,N-diallyl-5-(benzyloxy)-3-((tert-butyldimethylsilyl)oxy)pentanethioamide

Base Information

Chemical Name:(R)-N,N-diallyl-5-(benzyloxy)-3-((tert-butyldimethylsilyl)oxy)pentanethioamide
CAS No.:1347738-07-1
Molecular Formula:C₂₄H₃₉NO₂SSi
Molecular Weight:433.731
Hs Code.:

Synonyms:(R)-N,N-diallyl-5-(benzyloxy)-3-((tert-butyldimethylsilyl)oxy)pentanethioamide

Suppliers and Price of (R)-N,N-diallyl-5-(benzyloxy)-3-((tert-butyldimethylsilyl)oxy)pentanethioamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemicals and raw materials
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Total 1 raw suppliers

Chemical Property of (R)-N,N-diallyl-5-(benzyloxy)-3-((tert-butyldimethylsilyl)oxy)pentanethioamide

Chemical Property:

Purity/Quality:: 98% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

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Technology Process of (R)-N,N-diallyl-5-(benzyloxy)-3-((tert-butyldimethylsilyl)oxy)pentanethioamide

There total 4 articles about (R)-N,N-diallyl-5-(benzyloxy)-3-((tert-butyldimethylsilyl)oxy)pentanethioamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

: 1331869-16-9
(R)-N,N-diallyl-5-(benzyloxy)-3-hydroxypentanethioamide

: 69739-34-0
t-butyldimethylsiyl triflate

: 1347738-07-1
(R)-N,N-diallyl-5-(benzyloxy)-3-((tert-butyldimethylsilyl)oxy)pentanethioamide

Guidance literature:: With 2,6-dimethylpyridine; In dichloromethane; at 0 - 20 ℃; for 3h;
DOI:10.1016/j.tet.2011.05.109

Reference yield:

: 1182707-33-0
N,N-diallylmethylmethanethioamide

: 1347738-07-1
(R)-N,N-diallyl-5-(benzyloxy)-3-((tert-butyldimethylsilyl)oxy)pentanethioamide

Guidance literature:: Multi-step reaction with 2 steps

1: (+)-1,2-bis((2S,5S)-2,5-diphenylphospholanyl)ethane; mesitylcopper(I) / N,N-dimethyl-formamide / 60 h / -60 °C / Inert atmosphere; Molecular sieve

2: 2,6-dimethylpyridine / dichloromethane / 3 h / 0 - 20 °C

With 2,6-dimethylpyridine; (+)-1,2-bis((2S,5S)-2,5-diphenylphospholanyl)ethane; mesitylcopper(I); In dichloromethane; N,N-dimethyl-formamide; 1: Aldol reaction;
DOI:10.1016/j.tet.2011.05.109

Reference yield:

: 19790-60-4
3-Benzyloxypropanal

: 1347738-07-1
(R)-N,N-diallyl-5-(benzyloxy)-3-((tert-butyldimethylsilyl)oxy)pentanethioamide

Guidance literature:: Multi-step reaction with 2 steps

1: (+)-1,2-bis((2S,5S)-2,5-diphenylphospholanyl)ethane; mesitylcopper(I) / N,N-dimethyl-formamide / 60 h / -60 °C / Inert atmosphere; Molecular sieve

2: 2,6-dimethylpyridine / dichloromethane / 3 h / 0 - 20 °C

With 2,6-dimethylpyridine; (+)-1,2-bis((2S,5S)-2,5-diphenylphospholanyl)ethane; mesitylcopper(I); In dichloromethane; N,N-dimethyl-formamide; 1: Aldol reaction;
DOI:10.1016/j.tet.2011.05.109