4-(4-chlorophenyl)-3,6-dimethoxypyridazine

Base Information

Chemical Name:4-(4-chlorophenyl)-3,6-dimethoxypyridazine
CAS No.:41374-00-9
Molecular Formula:C₁₂H₁₁ClN₂O₂
Molecular Weight:250.685
Hs Code.:

Synonyms:4-(4-chlorophenyl)-3,6-dimethoxypyridazine

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 4-(4-chlorophenyl)-3,6-dimethoxypyridazine

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Technology Process of 4-(4-chlorophenyl)-3,6-dimethoxypyridazine

There total 2 articles about 4-(4-chlorophenyl)-3,6-dimethoxypyridazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

: 4603-59-2
3,6-dimethoxypyridazine

: 637-87-6
1-Chloro-4-iodobenzene

: 41374-00-9
4-(4-chlorophenyl)-3,6-dimethoxypyridazine

Guidance literature:: 3,6-dimethoxypyridazine; With tetramethylpiperidinylzinc chloride lithium chloride; In tetrahydrofuran; at 25 - 90 ℃; Inert atmosphere; Microwave irradiation;

1-Chloro-4-iodobenzene; With palladium bis(dibenzylideneacetone)palladium⁽⁰⁾; trifuran-2-yl-phosphane; In tetrahydrofuran; at 50 ℃; for 6h; chemoselective reaction; Inert atmosphere;
DOI:10.1021/jo100884u