N1-Methyladenosine

Base Information

Chemical Name:N1-Methyladenosine
CAS No.:15763-06-1
Molecular Formula:C₁₁H₁₅N₅O₄
Molecular Weight:281.271
Hs Code.:29389090
NSC Number:92165
Mol file:15763-06-1.mol

Synonyms:1-methyladenosine;N(1)-methyladenosine

Suppliers and Price of N1-Methyladenosine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
1-MethylAdenosine
250mg
$ 180.00

TRC
1-MethylAdenosine
100mg
$ 95.00

Medical Isotopes, Inc.
N1-Methyladenosine
100 mg
$ 395.00

Crysdot
(2R,3R,4S,5R)-2-(6-Amino-1-methyl-1H-purin-9(2H)-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol 95%
250mg
$ 193.00

Crysdot
(2R,3R,4S,5R)-2-(6-Amino-1-methyl-1H-purin-9(2H)-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol 95%
1g
$ 485.00

ChemScene
1-Methyladenosine 98.16%
50mg
$ 60.00

Chemenu
(2R,3R,4S,5R)-2-(6-Amino-1-methyl-1H-purin-9(2H)-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol 95%
1g
$ 458.00

Cayman Chemical
1-methyl Adenosine ≥98%
100mg
$ 78.00

Cayman Chemical
1-methyl Adenosine ≥98%
50mg
$ 50.00

Cayman Chemical
1-methyl Adenosine ≥98%
25mg
$ 37.00

Total 27 raw suppliers

Chemical Property of N1-Methyladenosine

Chemical Property:

Vapor Pressure:3.84E-11mmHg at 25°C
Refractive Index:1.823
Boiling Point:655.4 °C at 760 mmHg
PKA:13.24±0.70(Predicted)
Flash Point:350.2 °C
PSA：129.41000
Density:1.88 g/cm³
LogP:-2.03950
Storage Temp.:−20°C
Solubility.:DMSO (Slightly), Water (Slightly, Sonicated)
XLogP3:-1
Hydrogen Bond Donor Count:4
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:2
Exact Mass:281.11240398
Heavy Atom Count:20
Complexity:433

Purity/Quality:

99%, ^*data from raw suppliers

1-MethylAdenosine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:
Safety Statements: 24/25

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

Canonical SMILES:CN1C=NC2=C(C1=N)N=CN2C3C(C(C(O3)CO)O)O
Description 1-Methyladenosine is a modified nucleoside generated by the processing of tRNA by methyltransferases. The urinary excretion of 1-methyladenosine is elevated in several forms of cancer, supporting its use as a biomarker in early detection. It can also be monitored in serum. Urinary levels of 1-methyladenosine also increase during active rheumatoid arthritis.
Uses 1-Methyl Adenosine is a modified adenosine molecule created through the processing of tRNA by methyltransferases. The presence seen to be elevated in the urinary excretion of cancer patients. Thus it may be an early diagnosis biomarker.

Technology Process of N1-Methyladenosine

There total 11 articles about N1-Methyladenosine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

: C₁₂H₁₇N₅O₄

: 15763-06-1
1-methyladenosine

Guidance literature:: With manganese(IV) oxide; C₁₇H₂₀N₄O₉P^(1-)*Na⁽¹⁺⁾; oxygen; In water; acetonitrile; at 20 ℃; for 7h; under 760.051 Torr; chemoselective reaction; Irradiation;
DOI:10.1002/anie.201900901