(S)-6-aza-spiro[2.5]octan-4-ol hydrochloride

Base Information

Chemical Name:(S)-6-aza-spiro[2.5]octan-4-ol hydrochloride
CAS No.:1103501-89-8
Molecular Formula:C₇H₁₃NO*ClH
Molecular Weight:163.647
Hs Code.:

Synonyms:(S)-6-aza-spiro[2.5]octan-4-ol hydrochloride

Suppliers and Price of (S)-6-aza-spiro[2.5]octan-4-ol hydrochloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Synthonix
(4S)-6-Azaspiro[2.5]octan-4-olhydrochloride 95+%
1g
$ 1730.00

Crysdot
(S)-6-Azaspiro[2.5]octan-4-olhydrochloride 95+%
1g
$ 1695.00

Chemenu
(S)-6-Azaspiro[2.5]octan-4-olhydrochloride 95%
1g
$ 1597.00

Total 4 raw suppliers

Chemical Property of (S)-6-aza-spiro[2.5]octan-4-ol hydrochloride

Chemical Property:

Purity/Quality:

97% ^*data from raw suppliers

(4S)-6-Azaspiro[2.5]octan-4-olhydrochloride 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (S)-6-aza-spiro[2.5]octan-4-ol hydrochloride

There total 10 articles about (S)-6-aza-spiro[2.5]octan-4-ol hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 1101840-73-6
(S)-4-hydroxy-6-aza-spiro[2.5]octane-6-carboxylic acid tert-butyl ester

: 1103501-89-8,955028-68-9
(S)-6-aza-spiro[2.5]octan-4-ol hydrochloride

Guidance literature:: With hydrogenchloride; In 1,4-dioxane; ethanol; at 20 ℃; for 1h;

Reference yield:

: 1101840-81-6
(S)-6-Benzyl-6-aza-spiro[2.5]octan-4-ol

: 1103501-89-8,955028-68-9
(S)-6-aza-spiro[2.5]octan-4-ol hydrochloride

Guidance literature:: (S)-6-Benzyl-6-aza-spiro[2.5]octan-4-ol; With hydrogen; Pd-BaSO₄; In methanol;

With di-tert-butyl dicarbonate; triethylamine; In methanol;

With hydrogenchloride; In ethyl acetate; Product distribution / selectivity;

Reference yield:

: 159635-22-0
3-hydroxy-4-methylene-1-piperidinecarboxylic acid 1,1-dimethylethyl ester

: 1103501-89-8,955028-68-9
(S)-6-aza-spiro[2.5]octan-4-ol hydrochloride

Guidance literature:: Multi-step reaction with 4 steps

1.1: diethylzinc / toluene; 1,2-dichloro-ethane / 0.25 h / 0 °C / Inert atmosphere

1.2: 0.5 h / 0 °C / Inert atmosphere

2.1: oxalyl dichloride; dimethyl sulfoxide / dichloromethane / -70 - -60 °C

2.2: 0.17 h / -60 °C

3.1: sodium hydroxide; magnesium(II) chloride hexahydrate; α-D-glucose monohydrate / ketoreductase KRED-NADH-117; glucose dehydrogenase GDH-102 / 35 °C / pH 6.5 / Aqueous buffer

4.1: hydrogenchloride / 1,4-dioxane; ethanol / 1 h / 20 °C

With hydrogenchloride; oxalyl dichloride; magnesium(II) chloride hexahydrate; diethylzinc; α-D-glucose monohydrate; dimethyl sulfoxide; sodium hydroxide; ketoreductase KRED-NADH-117; glucose dehydrogenase GDH-102; In 1,4-dioxane; ethanol; dichloromethane; 1,2-dichloro-ethane; toluene; 2.1: Swern Oxidation / 2.2: Swern Oxidation;