3-({4-[(5-Chloro-1,3-benzodioxol-4-yl)amino]pyrimidin-2-yl}amino)-N,N-dimethylbenzamide

Base Information

Chemical Name:3-({4-[(5-Chloro-1,3-benzodioxol-4-yl)amino]pyrimidin-2-yl}amino)-N,N-dimethylbenzamide
CAS No.:945394-92-3
Molecular Formula:C₂₀H₁₈ClN₅O₃
Molecular Weight:411.848
Hs Code.:

Synonyms:3-({4-[(5-Chloro-1,3-benzodioxol-4-yl)amino]pyrimidin-2-yl}amino)-N,N-dimethylbenzamide

Suppliers and Price of 3-({4-[(5-Chloro-1,3-benzodioxol-4-yl)amino]pyrimidin-2-yl}amino)-N,N-dimethylbenzamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 3-({4-[(5-Chloro-1,3-benzodioxol-4-yl)amino]pyrimidin-2-yl}amino)-N,N-dimethylbenzamide

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 3-({4-[(5-Chloro-1,3-benzodioxol-4-yl)amino]pyrimidin-2-yl}amino)-N,N-dimethylbenzamide

There total 4 articles about 3-({4-[(5-Chloro-1,3-benzodioxol-4-yl)amino]pyrimidin-2-yl}amino)-N,N-dimethylbenzamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 945396-75-8
3-({4-[(5-Chloro-1,3-benzodioxol-4-yl)amino]pyrimidin-2-yl}amino)benzoyl chloride

: 124-40-3
dimethyl amine

: 945394-92-3
3-({4-[(5-Chloro-1,3-benzodioxol-4-yl)amino]pyrimidin-2-yl}amino)-N,N-dimethylbenzamide

Guidance literature:: In tetrahydrofuran; at 17 - 25 ℃; for 2h;

Reference yield:

: 945396-72-5
2-chloro-N-(5-chlorobenzo[d][1,3]dioxol-4-yl)pyrimidin-4-amine

: 945394-92-3
3-({4-[(5-Chloro-1,3-benzodioxol-4-yl)amino]pyrimidin-2-yl}amino)-N,N-dimethylbenzamide

Guidance literature:: Multi-step reaction with 3 steps

1: hydrogenchloride / 1,4-dioxane; N,N-dimethyl acetamide / 4 h / 96 °C

2: N,N-dimethyl-formamide; thionyl chloride / 2 h / 0 °C

3: tetrahydrofuran / 2 h / 17 - 25 °C

With hydrogenchloride; thionyl chloride; N,N-dimethyl-formamide; In tetrahydrofuran; 1,4-dioxane; N,N-dimethyl acetamide;

Reference yield:

: 379228-45-2
5-chlorobenzo[d][1,3]dioxolcyclopenten-4-amine

: 945394-92-3
3-({4-[(5-Chloro-1,3-benzodioxol-4-yl)amino]pyrimidin-2-yl}amino)-N,N-dimethylbenzamide

Guidance literature:: Multi-step reaction with 4 steps

1: sodium hydride / N,N-dimethyl acetamide; mineral oil / 0 - 25 °C

2: hydrogenchloride / 1,4-dioxane; N,N-dimethyl acetamide / 4 h / 96 °C

3: N,N-dimethyl-formamide; thionyl chloride / 2 h / 0 °C

4: tetrahydrofuran / 2 h / 17 - 25 °C

With hydrogenchloride; thionyl chloride; sodium hydride; N,N-dimethyl-formamide; In tetrahydrofuran; 1,4-dioxane; N,N-dimethyl acetamide; mineral oil;