dimethyl 5-[4-methoxycarbonyl-2-(4-octadecanoylaminobenzoylamino)phenoxy]isophthalate

Base Information

• Chemical Name: dimethyl 5-[4-methoxycarbonyl-2-(4-octadecanoylaminobenzoylamino)phenoxy]isophthalate
• CAS No.: 270064-55-6
• Molecular Formula: C₄₃H₅₆N₂O₉
• Molecular Weight: 744.926
• Mol file: 270064-55-6.mol

Synonyms:dimethyl 5-[4-methoxycarbonyl-2-(4-octadecanoylaminobenzoylamino)phenoxy]isophthalate

Chemical Property of dimethyl 5-[4-methoxycarbonyl-2-(4-octadecanoylaminobenzoylamino)phenoxy]isophthalate

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of dimethyl 5-[4-methoxycarbonyl-2-(4-octadecanoylaminobenzoylamino)phenoxy]isophthalate

There total 9 articles about dimethyl 5-[4-methoxycarbonyl-2-(4-octadecanoylaminobenzoylamino)phenoxy]isophthalate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 58.2%

Stearoyl chloride (112-76-5) + 5-[2-(4-amino-benzoylamino)-4-methoxycarbonyl-phenoxy]-isophthalic acid dimethyl ester → dimethyl 5-[4-methoxycarbonyl-2-(4-octadecanoylaminobenzoylamino)phenoxy]isophthalate (270064-55-6)

Guidance literature:

With triethylamine; In chloroform; at 20 ℃; for 21h;

DOI:10.1016/S0968-0896(01)00023-2

Reference yield:

4-nitro-benzoyl chloride (122-04-3) → dimethyl 5-[4-methoxycarbonyl-2-(4-octadecanoylaminobenzoylamino)phenoxy]isophthalate (270064-55-6)

Guidance literature:

Multi-step reaction with 3 steps

1: 72.9 percent / Et₃N / CHCl₃ / 20 °C

2: H₂ / Pd/C / dioxane; methanol / 20 °C

3: 58.2 percent / Et₃N / CHCl₃ / 21 h / 20 °C

With hydrogen; triethylamine; palladium on activated charcoal; In 1,4-dioxane; methanol; chloroform;

DOI:10.1016/S0968-0896(01)00023-2

Reference yield:

dimethyl 5-[4-methoxycarbonyl-2-(4-nitrobenzoylamino)phenoxy]isophthalate (270064-54-5) → dimethyl 5-[4-methoxycarbonyl-2-(4-octadecanoylaminobenzoylamino)phenoxy]isophthalate (270064-55-6)

Guidance literature:

Multi-step reaction with 2 steps

1: H₂ / Pd/C / dioxane; methanol / 20 °C

2: 58.2 percent / Et₃N / CHCl₃ / 21 h / 20 °C

With hydrogen; triethylamine; palladium on activated charcoal; In 1,4-dioxane; methanol; chloroform;

DOI:10.1016/S0968-0896(01)00023-2

upstream raw materials:

Stearoyl chloride

sodium stearate

4-nitro-benzoyl chloride

dimethyl 5-[4-methoxycarbonyl-2-(4-nitrobenzoylamino)phenoxy]isophthalate