Chemical Property of Phthalylsulfathiazole
Chemical Property:
- Vapor Pressure:3.01E-14mmHg at 25°C
- Melting Point:198-204 °C
- Refractive Index:1.6390 (estimate)
- Boiling Point:579oC at 760 mmHg
- PKA:3.40±0.36(Predicted)
- Flash Point:304oC
- PSA：162.08000
- Density:1.597 g/cm3
- LogP:4.12120
- Storage Temp.:-20°C
- Solubility.:Practically insoluble in water, freely soluble in dimethylformamide, slightly soluble in acetone and in ethanol (96 per cent).
- Water Solubility.:400mg/L at 28℃
- XLogP3:1.1
- Hydrogen Bond Donor Count:3
- Hydrogen Bond Acceptor Count:8
- Rotatable Bond Count:6
- Exact Mass:403.02966287
- Heavy Atom Count:27
- Complexity:643
- Purity/Quality:
-
99% up by HPLC *data from raw suppliers
Phthalylsulfathiazole *data from reagent suppliers
Safty Information:
- Pictogram(s):
- Hazard Codes:
- Safety Statements:
24/25
- MSDS Files:
-
SDS file from LookChem
Useful:
- Canonical SMILES:C1=CC=C(C(=C1)C(=O)NC2=CC=C(C=C2)S(=O)(=O)NC3=NC=CS3)C(=O)O
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Uses
Phthalylsulfathiazole is a sulfonamide antibacterial drug with similar and stronger effects than Sulfaguanidine and Succinylsulfathiazole. It is rarely absorbed orally and slowly decomposes in the intestine to release Sulfathiazole and exert intestinal antibacterial effects, and is used in the treatment of dysentery, colitis, and gastroenteritis.
