methyl (2S)-3-[2-(2,6-dichlorophenyl)-6-quinolyl]-2-[(3,5-dichloropyridine-4-carbonyl)amino]propanoate

Base Information

Chemical Name:methyl (2S)-3-[2-(2,6-dichlorophenyl)-6-quinolyl]-2-[(3,5-dichloropyridine-4-carbonyl)amino]propanoate
CAS No.:916887-25-7
Molecular Formula:C₂₅H₁₇Cl₄N₃O₃
Molecular Weight:549.24
Hs Code.:

Synonyms:methyl (2S)-3-[2-(2,6-dichlorophenyl)-6-quinolyl]-2-[(3,5-dichloropyridine-4-carbonyl)amino]propanoate

Suppliers and Price of methyl (2S)-3-[2-(2,6-dichlorophenyl)-6-quinolyl]-2-[(3,5-dichloropyridine-4-carbonyl)amino]propanoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of methyl (2S)-3-[2-(2,6-dichlorophenyl)-6-quinolyl]-2-[(3,5-dichloropyridine-4-carbonyl)amino]propanoate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of methyl (2S)-3-[2-(2,6-dichlorophenyl)-6-quinolyl]-2-[(3,5-dichloropyridine-4-carbonyl)amino]propanoate

There total 9 articles about methyl (2S)-3-[2-(2,6-dichlorophenyl)-6-quinolyl]-2-[(3,5-dichloropyridine-4-carbonyl)amino]propanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

: 623144-30-9
methyl (2S)-2-[(tert-butoxycarbonyl)amino]-3-[2-(2,6-dichlorophenyl)-6-quinolinyl]-propanoate

: 229328-97-6
3,5-dichloroisonicotinoyl chloride

: 916887-25-7
methyl (2S)-3-[2-(2,6-dichlorophenyl)-6-quinolyl]-2-[(3,5-dichloropyridine-4-carbonyl)amino]propanoate

Guidance literature:: methyl (2S)-2-[(tert-butoxycarbonyl)amino]-3-[2-(2,6-dichlorophenyl)-6-quinolinyl]-propanoate; With trifluoroacetic acid; In dichloromethane; at 20 ℃;

3,5-dichloroisonicotinoyl chloride; With triethylamine; In dichloromethane; at -10 - 20 ℃; for 1.16h;

Reference yield: 56.0%

: C₂₉H₂₆Cl₄N₄O₄

: 916887-25-7
methyl (2S)-3-[2-(2,6-dichlorophenyl)-6-quinolyl]-2-[(3,5-dichloropyridine-4-carbonyl)amino]propanoate

Guidance literature:: With oxygen; acetic acid; at 75 ℃; for 72h; Large scale;
DOI:10.1021/acs.oprd.9b00421

Reference yield: 30.0%

: methyl (2S)-3-(4-aminophenyl)-2-[(3,5-dichloropyridine-4-carbonyl)amino]propanoate

: 111-34-2,92680-80-3
-butyl vinyl ether

: 83-38-5
2,6-dichlorobenzaldehyde

: 916887-25-7
methyl (2S)-3-[2-(2,6-dichlorophenyl)-6-quinolyl]-2-[(3,5-dichloropyridine-4-carbonyl)amino]propanoate

Guidance literature:: methyl (2S)-3-(4-aminophenyl)-2-[(3,5-dichloropyridine-4-carbonyl)amino]propanoate; -butyl vinyl ether; 2,6-dichlorobenzaldehyde; In 2,2,2-trifluoroethanol; at 50 ℃; for 2.5h; Inert atmosphere;

In 2,2,2-trifluoroethanol; at 10 - 20 ℃; Inert atmosphere;

With acetic acid; In toluene; at 100 ℃; for 13h;
DOI:10.1021/acs.oprd.9b00421