(4Z)-4-[hydroxy(phenyl)methylidene]dihydrofuran-2,3-dione

Base Information

Chemical Name:(4Z)-4-[hydroxy(phenyl)methylidene]dihydrofuran-2,3-dione
CAS No.:7478-57-1
Molecular Formula:C11H8 O4
Molecular Weight:204.182
Hs Code.:
NSC Number:402941
DSSTox Substance ID:DTXSID30419883
Wikidata:Q82231101

Synonyms:7478-57-1;NSC402941;ST047361;ChemDiv2_001079;Oprea1_462096;SCHEMBL21110925;DTXSID30419883;HMS1372B01;STL514297;AKOS024281652;AKOS030493574;NSC-402941;AB00097093-01;SR-01000521995;SR-01000521995-1;(4Z)-4-[hydroxy(phenyl)methylidene]dihydrofuran-2,3-dione

Suppliers and Price of (4Z)-4-[hydroxy(phenyl)methylidene]dihydrofuran-2,3-dione

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 5 raw suppliers

Chemical Property of (4Z)-4-[hydroxy(phenyl)methylidene]dihydrofuran-2,3-dione

Chemical Property:

Vapor Pressure:3.2E-06mmHg at 25°C
Boiling Point:372.9°Cat760mmHg
Flash Point:151.1°C
Density:1.443g/cm³
XLogP3:1.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:1
Exact Mass:204.04225873
Heavy Atom Count:15
Complexity:324

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1C(=C(C2=CC=CC=C2)O)C(=O)C(=O)O1
Isomeric SMILES:C1/C(=C(\C2=CC=CC=C2)/O)/C(=O)C(=O)O1

Technology Process of (4Z)-4-[hydroxy(phenyl)methylidene]dihydrofuran-2,3-dione

There total 5 articles about (4Z)-4-[hydroxy(phenyl)methylidene]dihydrofuran-2,3-dione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 47.8%

: 50-00-0,30525-89-4,61233-19-0
formaldehyd

: 20577-73-5
methyl 4-phenyl-2,4-dioxobutanoate

: 7478-57-1
4-benzoyl-3-hydroxy-2,5-dihydrofuran-2-one

Guidance literature:: With potassium carbonate; In 1,4-dioxane; water; at 20 ℃; for 10h;
DOI:10.1007/BF02524633

Reference yield: 21.0%

: 50-00-0,30525-89-4,61233-19-0
formaldehyd

: Methyl benzoylpyruvate sodium

: 7478-57-1
4-benzoyl-3-hydroxy-2,5-dihydrofuran-2-one

Guidance literature:: With water; sodium hydrogencarbonate; at 0 ℃; for 2h;
DOI:10.1016/S0014-827X(97)00012-8

Reference yield:

: 50-00-0,30525-89-4,61233-19-0
formaldehyd

: 6296-54-4
ethyl 2,4-dioxo-4-phenylbutyrate

: 7478-57-1
4-benzoyl-3-hydroxy-2,5-dihydrofuran-2-one

Guidance literature:: With sodium formate; In diethyl ether; water; at 0 - 20 ℃; for 1h; Inert atmosphere; Schlenk technique;
DOI:10.1021/acs.joc.1c02156